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    <title>lab-test</title>
    <link>https://www.csbiology.org</link>
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      <title>Post-Doctoral Fellowship in Systems Immunology</title>
      <link>https://www.csbiology.org/post-doctoral-fellowship-in-systems-immunology</link>
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            Come work with us!
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           Job Information
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           Organisation/Company
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           FAPESP - São Paulo Research Foundation
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           Research Field
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           Medical sciences
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           Researcher Profile
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           Established Researcher (R3)
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           Country
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           Brazil
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           Application Deadline
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           15 Feb 2026 - 23:59 (UTC)
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           Type of Contract
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           To be defined
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           Is the job funded through the EU Research Framework Programme?
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           Not funded by a EU programme
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           Is the Job related to staff position within a Research Infrastructure?
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           No
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           Offer Description
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           The position is part of the subproject coordinated by Prof. Helder Nakaya (Albert Einstein Israeli Institute of Education and Research), focused on identifying shared cellular and molecular signatures across autoimmune and inflammatory diseases, including lupus, arthritis, Crohn’s disease, psoriasis, and ulcerative colitis. The work is fully in person in São Paulo and involves single-cell and spatial transcriptomics analysis, integration of multi-disease datasets, investigation of cell–cell communication, and the development of computational tools to understand the immunological mechanisms that drive inflammation.
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           We are looking for candidates who obtained their PhD within the last 7 years in bioinformatics, computational biology, immunology, molecular biology, data science, statistics, or related fields, with demonstrated experience in single-cell RNA sequencing (scRNA seq) analysis, data and multiomics integration, and cell type annotation; proficiency in R or Python; and excellent English. Experience with spatial transcriptomics and immunology of autoimmune diseases is desirable.
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           Interested candidates should send a motivation letter, CV summary according to the 
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    &lt;a href="https://fapesp.br/en/6351" target="_blank"&gt;&#xD;
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            model
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            established by FAPESP (the São Paulo Research Foundation, grantor institution), and contact information for two referees in a single PDF file to 
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    &lt;a href="mailto:csbl.assistant@gmail.com" target="_blank"&gt;&#xD;
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            csbl.assistant@gmail.com
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            with the subject line “Postdoc Autoimmune Fellowship Einstein”.
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           The fellow will develop his/her activities at the Computational System Biology Laboratory (CSBL) based at InovaUSP, the University of São Paulo's Innovation Center, located at USP's main campus in São Paulo city, Brazil.
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           This opportunity is open to candidates of any nationality. The selected candidate will receive a FAPESP Post-Doctoral fellowship in the amount of R$ 12,570.00 monthly and a research contingency fund, equivalent to 10% of the annual value of the fellowship which should be spent on items directly related to the research activity. 
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      <pubDate>Mon, 12 Jan 2026 12:39:49 GMT</pubDate>
      <guid>https://www.csbiology.org/post-doctoral-fellowship-in-systems-immunology</guid>
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      <title>Google Timeline Visualizer</title>
      <link>https://www.csbiology.org/google-timeline-visualizer</link>
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           How many km have you covered in recent years?
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            Download the HTML and run on your own computer (total privacy):
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    &lt;a href="https://irp.cdn-website.com/683b19b1/files/uploaded/GoogleTimelineVis.zip" target="_blank"&gt;&#xD;
      
           Zip file here
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            Versão em português (ferramental html e instruções):
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    &lt;a href="https://irp.cdn-website.com/683b19b1/files/uploaded/Ferramenta_e_instruc-o-es.zip" target="_blank"&gt;&#xD;
      
           Arquivo Zip
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      <pubDate>Thu, 11 Dec 2025 20:01:15 GMT</pubDate>
      <guid>https://www.csbiology.org/google-timeline-visualizer</guid>
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      <title>Distribuição da população urbana no Brasil em 3D</title>
      <link>https://www.csbiology.org/distribuicao-da-populacao-urbana-no-brasil-em-3d</link>
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           Como se distribui a população urbana no Brasil? 
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           Esta visualização tridimensional tenta responder a essa pergunta de forma intuitiva.
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           Cada pico representa uma célula hexagonal, e a altura e a cor indicam a densidade populacional. Embora o Brasil tenha dimensões continentais, reparem como a maior parte da população está concentrada na costa, especialmente nas regiões Sudeste e Nordeste.
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           A imagem foi criada em R com uma combinação de pacotes como rayshader, rayrender, sf, stars, magick e geobr. 
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           Em breve iremos usar essa mesma abordagem para representar dados de saúde. Uma visualização espacial linda e intuitiva pode fazer a diferença, né?
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           Os dados são de 2023 e estão disponíveis publicamente em data.humdata.org. 
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            A imagem em alta resolução está aqui:
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    &lt;a href="https://drive.google.com/file/d/1GbO8BYpPp7EZsW0aVP_7MSynkVKpdYpo/view?usp=sharing"&gt;&#xD;
      
           link
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      <pubDate>Mon, 14 Jul 2025 18:34:42 GMT</pubDate>
      <author>hnakaya@gmail.com (Helder Nakaya)</author>
      <guid>https://www.csbiology.org/distribuicao-da-populacao-urbana-no-brasil-em-3d</guid>
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      <title>Momento nostalgia</title>
      <link>https://www.csbiology.org/momento-nostalgia</link>
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           Preparando a palestra de amanhã e me sentindo muito velho. Ajudar a desbravar o novo mundo dos RNAs não codificadores longos foi algo estressante para um aluno que precisava defender sua tese mas foi muito empolgante!
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            Artigo de divulgação científica que publicamos na Ciência Hoje em 2006:
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           link
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      <pubDate>Mon, 21 Oct 2024 15:03:00 GMT</pubDate>
      <author>hnakaya@gmail.com (Helder Nakaya)</author>
      <guid>https://www.csbiology.org/momento-nostalgia</guid>
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      <title>One Health Postdoc position</title>
      <link>https://www.csbiology.org/posdoc-em-one-health</link>
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           Post doctoral position open in One Health project
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            We're hiring! The Computational Systems Biology Laboratory is looking for a motivated postdoc to join our Horizon Europe / Innovate UK-funded One Health project. The focus is on vaccine development and integrated host-response analysis for diseases affecting large animals like horses and pigs (e.g., African horse sickness virus and foot-and-mouth disease virus). This position involves working with systems immunology, RNAseq, scRNAseq, and proteomics data analysis.
            &#xD;
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            This is an on-site position based in São Paulo, with the opportunity to collaborate with international teams in Surrey and across Europe.
            &#xD;
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            If you're interested, apply here:
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    &lt;a href="https://forms.gle/pb8uUqEcSWsTieoK9" target="_blank"&gt;&#xD;
      
           link
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      <pubDate>Mon, 14 Oct 2024 18:23:16 GMT</pubDate>
      <author>hnakaya@gmail.com (Helder Nakaya)</author>
      <guid>https://www.csbiology.org/posdoc-em-one-health</guid>
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      <title>The Landscape of Brazilian Immunology PhDs - part 1</title>
      <link>https://www.csbiology.org/the-landscape-of-brazilian-immunology-phds-part-1</link>
      <description />
      <content:encoded>&lt;div data-rss-type="text"&gt;&#xD;
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           We analyzed 7,315,181 Brazilian CVs and found 6,275 immunologists with PhD
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            Download the top 100 immunologists here:
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    &lt;a href="/"&gt;&#xD;
      
           link
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      <pubDate>Tue, 16 Apr 2024 19:51:35 GMT</pubDate>
      <author>hnakaya@gmail.com (Helder Nakaya)</author>
      <guid>https://www.csbiology.org/the-landscape-of-brazilian-immunology-phds-part-1</guid>
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      <title>Oficina para vídeos de divulgação científica</title>
      <link>https://www.csbiology.org/oficina-para-videos-de-divulgacao-cientifica</link>
      <description />
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           Oficina da pós-graduação em Ciências da Saúde do Einstein
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            ﻿
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      &lt;br/&gt;&#xD;
    &lt;/span&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      
           O Programa de Pós-Graduação stricto sensu em Ciências da Saúde, do Einstein, promoverá “Oficina de Comunicação Científica”, ministrada por 
          &#xD;
    &lt;/span&gt;&#xD;
    &lt;a href="https://www.linkedin.com/in/ACoAAA4hjuYBi89TYnNnOr1270guitHksdVkrj8" target="_blank"&gt;&#xD;
      
           Helder Nakaya
          &#xD;
    &lt;/a&gt;&#xD;
    &lt;span&gt;&#xD;
      
           , pesquisador sênior e docente do PPG. Será gratuito, no formato on-line, em quatro encontros (26/08, 02/09, 09/09 e 16/09), das 14h às 15h30, para alunos de pós-graduação de todo o Brasil.
           &#xD;
      &lt;br/&gt;&#xD;
      &lt;br/&gt;&#xD;
      
           Inscrevam-se! 
          &#xD;
    &lt;/span&gt;&#xD;
    &lt;a href="https://lnkd.in/dYSdya6V" target="_blank"&gt;&#xD;
      
           https://lnkd.in/dYSdya6V
          &#xD;
    &lt;/a&gt;&#xD;
    &lt;span&gt;&#xD;
      &lt;br/&gt;&#xD;
      
           PPG em Ciências da Saúde: 
          &#xD;
    &lt;/span&gt;&#xD;
    &lt;a href="https://lnkd.in/dWzG-8s" target="_blank"&gt;&#xD;
      
           https://lnkd.in/dWzG-8s
          &#xD;
    &lt;/a&gt;&#xD;
    &lt;span&gt;&#xD;
      &lt;br/&gt;&#xD;
      
           Pesquisa Einstein: 
          &#xD;
    &lt;/span&gt;&#xD;
    &lt;a href="http://www.einstein.br/pesquisa" target="_blank"&gt;&#xD;
      
           www.einstein.br/pesquisa
          &#xD;
    &lt;/a&gt;&#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;</content:encoded>
      <enclosure url="https://irp.cdn-website.com/683b19b1/dms3rep/multi/oficina.png" length="199142" type="image/png" />
      <pubDate>Fri, 19 Aug 2022 18:55:35 GMT</pubDate>
      <author>hnakaya@gmail.com (Helder Nakaya)</author>
      <guid>https://www.csbiology.org/oficina-para-videos-de-divulgacao-cientifica</guid>
      <g-custom:tags type="string" />
      <media:content medium="image" url="https://irp.cdn-website.com/683b19b1/dms3rep/multi/oficina.png">
        <media:description>thumbnail</media:description>
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        <media:description>main image</media:description>
      </media:content>
    </item>
    <item>
      <title>Nobel Prize laureates which were important to IMMUNOLOGY</title>
      <link>https://www.csbiology.org/nobel-prize-laureates-which-were-important-to-immunology</link>
      <description />
      <content:encoded>&lt;div data-rss-type="text"&gt;&#xD;
  &lt;h3&gt;&#xD;
    &lt;span&gt;&#xD;
      
           Download high-resolution image from here (
          &#xD;
    &lt;/span&gt;&#xD;
    &lt;a href="https://irp.cdn-website.com/683b19b1/files/uploaded/Nobel_and_immunology.pdf" target="_blank"&gt;&#xD;
      
           PDF
          &#xD;
    &lt;/a&gt;&#xD;
    &lt;span&gt;&#xD;
      &lt;span&gt;&#xD;
        
            ,
           &#xD;
      &lt;/span&gt;&#xD;
    &lt;/span&gt;&#xD;
    &lt;a href="https://irp.cdn-website.com/683b19b1/files/uploaded/Nobel_and_immunology.jpg" target="_blank"&gt;&#xD;
      
           JPG
          &#xD;
    &lt;/a&gt;&#xD;
    &lt;span&gt;&#xD;
      &lt;span&gt;&#xD;
        
            ,
           &#xD;
      &lt;/span&gt;&#xD;
    &lt;/span&gt;&#xD;
    &lt;a href="https://irp.cdn-website.com/683b19b1/files/uploaded/Nobel_and_immunology.png" target="_blank"&gt;&#xD;
      
           PNG
          &#xD;
    &lt;/a&gt;&#xD;
    &lt;span&gt;&#xD;
      
           )
          &#xD;
    &lt;/span&gt;&#xD;
  &lt;/h3&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div&gt;&#xD;
  &lt;img src="https://irp.cdn-website.com/683b19b1/dms3rep/multi/immune+poster_v8.png"/&gt;&#xD;
&lt;/div&gt;</content:encoded>
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      <pubDate>Thu, 07 Jul 2022 18:24:34 GMT</pubDate>
      <author>hnakaya@gmail.com (Helder Nakaya)</author>
      <guid>https://www.csbiology.org/nobel-prize-laureates-which-were-important-to-immunology</guid>
      <g-custom:tags type="string" />
      <media:content medium="image" url="https://irp.cdn-website.com/683b19b1/dms3rep/multi/immune+poster_v8.jpg">
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    </item>
    <item>
      <title>Academic fields of study (Natural Sciences)</title>
      <link>https://www.csbiology.org/academic-fields-of-study-natural-sciences</link>
      <description />
      <content:encoded>&lt;div data-rss-type="text"&gt;&#xD;
  &lt;h3&gt;&#xD;
    &lt;span&gt;&#xD;
      
           Check the network of "fields of study"
          &#xD;
    &lt;/span&gt;&#xD;
  &lt;/h3&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div&gt;&#xD;
  &lt;img src="https://irp.cdn-website.com/683b19b1/dms3rep/multi/Fields_of_research_1.png"/&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      &lt;span&gt;&#xD;
        
            Use the interactive network:
           &#xD;
      &lt;/span&gt;&#xD;
    &lt;/span&gt;&#xD;
    &lt;a href="https://csbl-br.github.io/Fields_of_study/index.html" target="_blank"&gt;&#xD;
      
           click here
          &#xD;
    &lt;/a&gt;&#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;</content:encoded>
      <enclosure url="https://irp.cdn-website.com/683b19b1/dms3rep/multi/Fields_v1.jpg" length="598015" type="image/jpeg" />
      <pubDate>Tue, 05 Jul 2022 15:26:53 GMT</pubDate>
      <author>hnakaya@gmail.com (Helder Nakaya)</author>
      <guid>https://www.csbiology.org/academic-fields-of-study-natural-sciences</guid>
      <g-custom:tags type="string" />
      <media:content medium="image" url="https://irp.cdn-website.com/683b19b1/dms3rep/multi/Fields_v1.jpg">
        <media:description>thumbnail</media:description>
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    </item>
    <item>
      <title>Frequently used words in titles from Science and Nature articles</title>
      <link>https://www.csbiology.org/frquently-used-words-in-titles-from-science-and-nature-journals</link>
      <description />
      <content:encoded>&lt;div data-rss-type="text"&gt;&#xD;
  &lt;h3&gt;&#xD;
    &lt;span&gt;&#xD;
      
           If you have a great work in your hand, make sure to include some of these words in the title of your manuscript before submitting to Science or Nature.
          &#xD;
    &lt;/span&gt;&#xD;
  &lt;/h3&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div&gt;&#xD;
  &lt;img src="https://irp.cdn-website.com/683b19b1/dms3rep/multi/Titles_v1.jpg"/&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      &lt;span&gt;&#xD;
        
            After analyzing 76,606 titles of the research articles published in Nature and Science between 1965 and 2020, we counted how many times each word (actually, we counted the word stem) was used in the titles.
           &#xD;
      &lt;/span&gt;&#xD;
    &lt;/span&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      &lt;br/&gt;&#xD;
    &lt;/span&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      &lt;span&gt;&#xD;
        
            The wordclouds show the most frequent words in 1965-1975 and in 2011-2020. Early in 1965, titles mentioning animals (rat, frog, mice, monkey, cat, chicken) were common. Interestingly, several titles back then utilized words such as Apollo, lunar, rock, and meteorite.
           &#xD;
      &lt;/span&gt;&#xD;
    &lt;/span&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      &lt;br/&gt;&#xD;
    &lt;/span&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      
           In recent years, titles often included words such genome, global, integration, regulation, and modulation. “Cell” is one word that was always highly present in titles!
          &#xD;
    &lt;/span&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      &lt;br/&gt;&#xD;
    &lt;/span&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      
           These words are not clickbait but they definitely attract our attention.
          &#xD;
    &lt;/span&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      &lt;br/&gt;&#xD;
    &lt;/span&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      &lt;span&gt;&#xD;
        
            Full data here:
           &#xD;
      &lt;/span&gt;&#xD;
    &lt;/span&gt;&#xD;
    &lt;a href="https://irp.cdn-website.com/683b19b1/files/uploaded/Science_and_Nature_ResearchArticles_1965to2020.xlsx" target="_blank"&gt;&#xD;
      
           link
          &#xD;
    &lt;/a&gt;&#xD;
    &lt;span&gt;&#xD;
      
           .
          &#xD;
    &lt;/span&gt;&#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;</content:encoded>
      <enclosure url="https://irp.cdn-website.com/683b19b1/dms3rep/multi/Titles_v1.jpg" length="368460" type="image/jpeg" />
      <pubDate>Mon, 04 Apr 2022 19:55:28 GMT</pubDate>
      <author>hnakaya@gmail.com (Helder Nakaya)</author>
      <guid>https://www.csbiology.org/frquently-used-words-in-titles-from-science-and-nature-journals</guid>
      <g-custom:tags type="string" />
      <media:content medium="image" url="https://irp.cdn-website.com/683b19b1/dms3rep/multi/Titles_v1.jpg">
        <media:description>thumbnail</media:description>
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    <item>
      <title>Livro "RNA" de Paulo Amaral e John Mattick</title>
      <link>https://www.csbiology.org/livro-rna-de-paulo-amaral-e-john-mattick</link>
      <description />
      <content:encoded>&lt;div data-rss-type="text"&gt;&#xD;
  &lt;h1&gt;&#xD;
    &lt;a href="/" target="_blank"&gt;&#xD;
      
           RNA, the Epicenter of Genetic Information
          &#xD;
    &lt;/a&gt;&#xD;
  &lt;/h1&gt;&#xD;
  &lt;h3&gt;&#xD;
    &lt;br/&gt;&#xD;
  &lt;/h3&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div&gt;&#xD;
  &lt;img src="https://irp.cdn-website.com/683b19b1/dms3rep/multi/9780367623920.jpg"/&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      
           Quando o genoma era tudo mato, muitas regiões do DNA eram consideradas lixo. Hoje, o livro que mostra tudo o que você precisa saber sobre essas moléculas maravilhosas chamadas "RNA" foi lançado pelo Paulo Amaral (@ppamaral) e John Mattick.
          &#xD;
    &lt;/span&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      &lt;br/&gt;&#xD;
    &lt;/span&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      
           Eu estava lá na primeira vez que o Paulo se deparou com elas e mergulhou de cabeça pra tentar entender o que diabos elas faziam no nosso genoma. Quem sintetizavam? O que elas regulavam?
          &#xD;
    &lt;/span&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      &lt;br/&gt;&#xD;
    &lt;/span&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      &lt;span&gt;&#xD;
        
            Escrevemos um artigo em português sobre esse DNA lixo que valia ouro (Ciência Hoje
           &#xD;
      &lt;/span&gt;&#xD;
    &lt;/span&gt;&#xD;
    &lt;a href="https://irp.cdn-website.com/683b19b1/files/uploaded/PRINT-Ciencia%20Hoje%20-%20O%20lixo%20que%20vale%20ouro.pdf" target="_blank"&gt;&#xD;
      
           link
          &#xD;
    &lt;/a&gt;&#xD;
    &lt;span&gt;&#xD;
      
           ). Até fiz um vídeo explicativo anos mais tarde (ver abaixo) e publicamos diversos artigos na área.
          &#xD;
    &lt;/span&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      &lt;br/&gt;&#xD;
    &lt;/span&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      &lt;span&gt;&#xD;
        
            Mas claro, muita ciência de ponta foi feita desde então e Paulo se tornou um dos maiores experts no mundo sobre RNAs não codificadores longos!
           &#xD;
      &lt;/span&gt;&#xD;
    &lt;/span&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      &lt;br/&gt;&#xD;
    &lt;/span&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      &lt;span&gt;&#xD;
        
            Agora saiu o livro que reúne tudo, absolutamente tudo o que se sabe (até anteontem pra ser honesto) sobre como os RNAs são, na verdade, os grandes personagens da biologia molecular! Parabéns, Paulo. Muito orgulho de ver essa obra de arte saindo!
           &#xD;
      &lt;/span&gt;&#xD;
    &lt;/span&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      &lt;br/&gt;&#xD;
    &lt;/span&gt;&#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;</content:encoded>
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      <pubDate>Tue, 29 Mar 2022 22:08:04 GMT</pubDate>
      <author>hnakaya@gmail.com (Helder Nakaya)</author>
      <guid>https://www.csbiology.org/livro-rna-de-paulo-amaral-e-john-mattick</guid>
      <g-custom:tags type="string" />
      <media:content medium="image" url="https://irp.cdn-website.com/683b19b1/dms3rep/multi/9780367623920.jpg">
        <media:description>thumbnail</media:description>
      </media:content>
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    </item>
    <item>
      <title>Brazil's top scientific collaborators in biomedical research</title>
      <link>https://www.csbiology.org/brazil-s-top-scientific-collaborators-in-biomedical-research</link>
      <description />
      <content:encoded>&lt;div data-rss-type="text"&gt;&#xD;
  &lt;h3&gt;&#xD;
    &lt;span&gt;&#xD;
      &lt;span&gt;&#xD;
        
            Table with the number of research articles from PubMed that had authors from more than 1 country:
           &#xD;
      &lt;/span&gt;&#xD;
    &lt;/span&gt;&#xD;
    &lt;a href="https://irp.cdn-website.com/683b19b1/files/uploaded/Collaborations_between_countries.xlsx" target="_blank"&gt;&#xD;
      
           click here
          &#xD;
    &lt;/a&gt;&#xD;
  &lt;/h3&gt;&#xD;
  &lt;h3&gt;&#xD;
    &lt;span&gt;&#xD;
      &lt;br/&gt;&#xD;
    &lt;/span&gt;&#xD;
  &lt;/h3&gt;&#xD;
  &lt;h3&gt;&#xD;
    &lt;span&gt;&#xD;
      
           Map below shows the countries whose scientists collaborated in at least 5,000 articles.
          &#xD;
    &lt;/span&gt;&#xD;
  &lt;/h3&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div&gt;&#xD;
  &lt;img src="https://irp.cdn-website.com/683b19b1/dms3rep/multi/Pairs_v2.png"/&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    
          Parágrafo Novo
         &#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;</content:encoded>
      <enclosure url="https://irp.cdn-website.com/683b19b1/dms3rep/multi/Pairs_v2.jpg" length="585043" type="image/jpeg" />
      <pubDate>Sun, 27 Mar 2022 18:06:09 GMT</pubDate>
      <author>hnakaya@gmail.com (Helder Nakaya)</author>
      <guid>https://www.csbiology.org/brazil-s-top-scientific-collaborators-in-biomedical-research</guid>
      <g-custom:tags type="string" />
      <media:content medium="image" url="https://irp.cdn-website.com/683b19b1/dms3rep/multi/Pairs_v2.jpg">
        <media:description>thumbnail</media:description>
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    </item>
    <item>
      <title>Research on COVID-19 (Brazil)</title>
      <link>https://www.csbiology.org/research-on-covid-19-brazil</link>
      <description />
      <content:encoded>&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      
           These are the Brazilian scientists who have published the highest number of articles related to COVID-19. Of the top 6 scientists, 5 were women!
           &#xD;
      &lt;br/&gt;&#xD;
    &lt;/span&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;br/&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      &lt;span&gt;&#xD;
        &lt;br/&gt;&#xD;
        
            (We analyzed nearly 120,000 COVID-19 articles with more than 10,000 authors from Brazil)
            &#xD;
        &lt;br/&gt;&#xD;
        &lt;br/&gt;&#xD;
        
            Check the table: 
           &#xD;
      &lt;/span&gt;&#xD;
    &lt;/span&gt;&#xD;
    &lt;a href="https://irp.cdn-website.com/683b19b1/files/uploaded/Authors_With_Publications_in_COVID-19_BR.xlsx" target="_blank"&gt;&#xD;
      
           link
          &#xD;
    &lt;/a&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      
           Reviews were excluded and there are authors with the same name
          &#xD;
    &lt;/span&gt;&#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;</content:encoded>
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      <pubDate>Thu, 17 Mar 2022 10:26:33 GMT</pubDate>
      <author>hnakaya@gmail.com (Helder Nakaya)</author>
      <guid>https://www.csbiology.org/research-on-covid-19-brazil</guid>
      <g-custom:tags type="string" />
      <media:content medium="image" url="https://irp.cdn-website.com/683b19b1/dms3rep/multi/Top_Scientists.jpg">
        <media:description>thumbnail</media:description>
      </media:content>
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      </media:content>
    </item>
    <item>
      <title>Top Research Priorities across Countries</title>
      <link>https://www.csbiology.org/top-research-priorities-across-countries</link>
      <description />
      <content:encoded>&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      
           Research topics which are among the top 100 research priorities across countries. 
           &#xD;
      &lt;br/&gt;&#xD;
    &lt;/span&gt;&#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div&gt;&#xD;
  &lt;img src="https://irp.cdn-website.com/683b19b1/dms3rep/multi/HIV_Infections.png"/&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      &lt;span&gt;&#xD;
        
            Donwload table with number of papers per topic per country
           &#xD;
      &lt;/span&gt;&#xD;
    &lt;/span&gt;&#xD;
    &lt;a href="https://docs.google.com/spreadsheets/d/1Pzkz_F1VAIKxuynII6OAtdfN404ISWJo/edit?usp=sharing&amp;amp;ouid=110708484835056451958&amp;amp;rtpof=true&amp;amp;sd=true" target="_blank"&gt;&#xD;
      
           here
          &#xD;
    &lt;/a&gt;&#xD;
    &lt;span&gt;&#xD;
      
           .
          &#xD;
    &lt;/span&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;br/&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      &lt;span&gt;&#xD;
        
            Donwload table with RANKING (by number of papers) of topics per country
           &#xD;
      &lt;/span&gt;&#xD;
    &lt;/span&gt;&#xD;
    &lt;a href="https://docs.google.com/spreadsheets/d/1Gh9WROT1j3lNyh4lvSiQaUA64keHdnUg/edit?usp=sharing&amp;amp;ouid=110708484835056451958&amp;amp;rtpof=true&amp;amp;sd=true" target="_blank"&gt;&#xD;
      
           here
          &#xD;
    &lt;/a&gt;&#xD;
    &lt;span&gt;&#xD;
      
           .
          &#xD;
    &lt;/span&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;br/&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      &lt;span&gt;&#xD;
        
            Download zip file containing the maps for selected topics
           &#xD;
      &lt;/span&gt;&#xD;
    &lt;/span&gt;&#xD;
    &lt;a href="https://drive.google.com/file/d/1tVbOn11knV85Qg5reULtig_5PqQ06xQH/view?usp=sharing" target="_blank"&gt;&#xD;
      
           here
          &#xD;
    &lt;/a&gt;&#xD;
    &lt;span&gt;&#xD;
      
           .
          &#xD;
    &lt;/span&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;br/&gt;&#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;</content:encoded>
      <enclosure url="https://irp.cdn-website.com/683b19b1/dms3rep/multi/COVID-19.png" length="119420" type="image/png" />
      <pubDate>Sat, 29 Jan 2022 14:48:39 GMT</pubDate>
      <author>hnakaya@gmail.com (Helder Nakaya)</author>
      <guid>https://www.csbiology.org/top-research-priorities-across-countries</guid>
      <g-custom:tags type="string" />
      <media:content medium="image" url="https://irp.cdn-website.com/683b19b1/dms3rep/multi/COVID-19.png">
        <media:description>thumbnail</media:description>
      </media:content>
      <media:content medium="image" url="https://irp.cdn-website.com/683b19b1/dms3rep/multi/COVID-19.png">
        <media:description>main image</media:description>
      </media:content>
    </item>
    <item>
      <title>Bolsas de Produtividade do CNPq 2021</title>
      <link>https://www.csbiology.org/bolsas-de-produtividade-do-cnpq-2021</link>
      <description />
      <content:encoded>&lt;div data-rss-type="text"&gt;&#xD;
  &lt;h3&gt;&#xD;
    &lt;span&gt;&#xD;
      &lt;span&gt;&#xD;
        
            Essas são as 25 instituições de pesquisas com mais indicações
           &#xD;
      &lt;/span&gt;&#xD;
    &lt;/span&gt;&#xD;
  &lt;/h3&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div&gt;&#xD;
  &lt;img src="https://irp.cdn-website.com/683b19b1/dms3rep/multi/PQ_CNPq_2021.JPG"/&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      &lt;span&gt;&#xD;
        
            PDF Original com resultado preliminar:
           &#xD;
      &lt;/span&gt;&#xD;
    &lt;/span&gt;&#xD;
    &lt;a href="https://irp.cdn-website.com/683b19b1/files/uploaded/ResultPreliminarPQ2021-1.pdf" target="_blank"&gt;&#xD;
      
           aqui
          &#xD;
    &lt;/a&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;br/&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      &lt;span&gt;&#xD;
        
            Tabela convertida:
           &#xD;
      &lt;/span&gt;&#xD;
    &lt;/span&gt;&#xD;
    &lt;a href="https://irp.cdn-website.com/683b19b1/files/uploaded/Produtividade_bolsas.xlsx" target="_blank"&gt;&#xD;
      
           aqui
          &#xD;
    &lt;/a&gt;&#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;</content:encoded>
      <enclosure url="https://irp.cdn-website.com/683b19b1/dms3rep/multi/PQ_CNPq_2021.JPG" length="38928" type="image/jpeg" />
      <pubDate>Sat, 18 Dec 2021 17:39:06 GMT</pubDate>
      <author>hnakaya@gmail.com (Helder Nakaya)</author>
      <guid>https://www.csbiology.org/bolsas-de-produtividade-do-cnpq-2021</guid>
      <g-custom:tags type="string" />
      <media:content medium="image" url="https://irp.cdn-website.com/683b19b1/dms3rep/multi/PQ_CNPq_2021.JPG">
        <media:description>thumbnail</media:description>
      </media:content>
      <media:content medium="image" url="https://irp.cdn-website.com/683b19b1/dms3rep/multi/PQ_CNPq_2021.JPG">
        <media:description>main image</media:description>
      </media:content>
    </item>
    <item>
      <title>PubMed Bibliometrics paper</title>
      <link>https://www.csbiology.org/pubmed-bibliometrics-paper</link>
      <description />
      <content:encoded>&lt;div data-rss-type="text"&gt;&#xD;
  &lt;h3&gt;&#xD;
    &lt;span&gt;&#xD;
      
           Analyzing 30M scientific articles from the Biomedical literature
          &#xD;
    &lt;/span&gt;&#xD;
  &lt;/h3&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div&gt;&#xD;
  &lt;img src="https://irp.cdn-website.com/683b19b1/dms3rep/multi/Journals_V2.JPG"/&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      
           Here is the list of current people working on it:
          &#xD;
    &lt;/span&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      &lt;span&gt;&#xD;
        
            André Guilherme @CostaMartinsAG
           &#xD;
      &lt;/span&gt;&#xD;
    &lt;/span&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      
           Helder Nakaya @helder_nakaya
          &#xD;
    &lt;/span&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;br/&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      &lt;span&gt;&#xD;
        
            List of first names:
           &#xD;
      &lt;/span&gt;&#xD;
    &lt;/span&gt;&#xD;
    &lt;a href="/"&gt;&#xD;
      
           download here
          &#xD;
    &lt;/a&gt;&#xD;
  &lt;/p&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;span&gt;&#xD;
      
           (Who can help identifying the gender of the names?)
          &#xD;
    &lt;/span&gt;&#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;</content:encoded>
      <enclosure url="https://irp.cdn-website.com/683b19b1/dms3rep/multi/PubMed-Logo.wine-cb24356b.png" length="24128" type="image/png" />
      <pubDate>Mon, 29 Nov 2021 22:02:12 GMT</pubDate>
      <author>hnakaya@gmail.com (Helder Nakaya)</author>
      <guid>https://www.csbiology.org/pubmed-bibliometrics-paper</guid>
      <g-custom:tags type="string" />
      <media:content medium="image" url="https://irp.cdn-website.com/683b19b1/dms3rep/multi/PubMed-Logo.wine-cb24356b.png">
        <media:description>thumbnail</media:description>
      </media:content>
      <media:content medium="image" url="https://irp.cdn-website.com/683b19b1/dms3rep/multi/PubMed-Logo.wine-cb24356b.png">
        <media:description>main image</media:description>
      </media:content>
    </item>
    <item>
      <title>Le Penseur Robot</title>
      <link>https://www.csbiology.org/le-penseur-robot</link>
      <description />
      <content:encoded>&lt;div data-rss-type="text"&gt;&#xD;
  &lt;h3&gt;&#xD;
    &lt;span&gt;&#xD;
      
           These images was conceived by Helder Nakaya and designed by Allan Rodrigo Nascimento de Carvalho. It depicts a robot thinking the same way as the Le Penseur (or The Thinker), a bronze sculpture by Auguste Rodin. The robot represents the artificial intelligence so common in our modern society.
          &#xD;
    &lt;/span&gt;&#xD;
  &lt;/h3&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div&gt;&#xD;
  &lt;img src="https://irp.cdn-website.com/683b19b1/dms3rep/multi/rodin_robot1.png"/&gt;&#xD;
&lt;/div&gt;</content:encoded>
      <enclosure url="https://irp.cdn-website.com/683b19b1/dms3rep/multi/rodin_robot1.png" length="227449" type="image/png" />
      <pubDate>Thu, 11 Nov 2021 17:42:27 GMT</pubDate>
      <author>hnakaya@gmail.com (Helder Nakaya)</author>
      <guid>https://www.csbiology.org/le-penseur-robot</guid>
      <g-custom:tags type="string" />
      <media:content medium="image" url="https://irp.cdn-website.com/683b19b1/dms3rep/multi/rodin_robot1.png">
        <media:description>thumbnail</media:description>
      </media:content>
      <media:content medium="image" url="https://irp.cdn-website.com/683b19b1/dms3rep/multi/rodin_robot1.png">
        <media:description>main image</media:description>
      </media:content>
    </item>
    <item>
      <title>Bolsa de PD em Bioinformática / Biologia de Sistemas (2021)</title>
      <link>https://www.csbiology.org/bolsa-de-pd-em-bioinformatica-biologia-de-sistemas-2021</link>
      <description />
      <content:encoded>&lt;div&gt;&#xD;
  &lt;img src="https://irp.cdn-website.com/683b19b1/dms3rep/multi/Vaga_CSBL_CRID-07a8ed00.png" alt=""/&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  
         Uma vaga de pós-doutorado em bioinformática / biologia de sistemas com foco em análise transcriptômica está disponível no Centro de Pesquisa em Doenças Inflamatórias – CRID (http://crid.fmrp.usp.br), um Centro de Pesquisa, Inovação e Difusão (CEPID) apoiado pela FAPESP com sede na Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo. O candidato bem-sucedido se juntará ao Laboratório de Biologia de Sistemas Computacional (CSBL, https://www.csbiology.org). As atividades serão supervisionadas pelo Prof. Helder Nakaya.
         &#xD;
  &lt;div&gt;&#xD;
    &lt;br/&gt;&#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;b&gt;&#xD;
      
           Responsabilidades
          &#xD;
    &lt;/b&gt;&#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;br/&gt;&#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;b&gt;&#xD;
      
           O candidato trabalhará nas dependências do CRID, localizado na USP de Ribeirão Preto.
          &#xD;
    &lt;/b&gt;&#xD;
    
          Espera-se que o bolsista desempenhe papel de liderança na análise de dados, que inclui a integração de dados ômicos e o desenvolvimento de modelos preditivos e hipóteses testáveis.
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;br/&gt;&#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    
          As responsabilidades específicas incluem:
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;br/&gt;&#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    
          - Desenvolvimento de protocolos de análise para conjuntos de dados internos e públicos de expressões gênicas;
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;br/&gt;&#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    
          - Desenvolvimento ou adaptação de ferramentas e scripts de software para atender às necessidades do projeto.
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;br/&gt;&#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;b&gt;&#xD;
      
           Requisitos
          &#xD;
    &lt;/b&gt;&#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;br/&gt;&#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    
          O candidato deverá ter experiência comprovada em pesquisa de bioinformática. A familiaridade com o trabalho em um ambiente Linux/Unix, além de fluência em linguagens de programação R ou Python, é necessária;
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;br/&gt;&#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    
          Por favor, envie seu currículo com informações de contato, uma carta de motivação e pelo menos 2 cartas de recomendação ao Prof. Helder Nakaya, e-mail: hnakaya@usp.br.
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;br/&gt;&#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    
          A vaga está aberta a brasileiros e estrangeiros. O selecionado receberá Bolsa de Pós-Doutorado da FAPESP no valor de R$ 7.373,10 mensais e Reserva Técnica equivalente a 10% do valor anual da bolsa para atender a despesas imprevistas e diretamente relacionadas à atividade de pesquisa.
          &#xD;
    &lt;br/&gt;&#xD;
    &lt;br/&gt;&#xD;
    
          https://fapesp.br/oportunidades/crid_%E2%80%93_centro_de_pesquisa_em_doencas_inflamatorias/4611/
         &#xD;
  &lt;/div&gt;&#xD;
&lt;/div&gt;</content:encoded>
      <enclosure url="https://irp.cdn-website.com/683b19b1/dms3rep/multi/Vaga_CSBL_CRID.png" length="56775" type="image/png" />
      <pubDate>Tue, 19 Oct 2021 14:16:15 GMT</pubDate>
      <author>hnakaya@gmail.com (Helder Nakaya)</author>
      <guid>https://www.csbiology.org/bolsa-de-pd-em-bioinformatica-biologia-de-sistemas-2021</guid>
      <g-custom:tags type="string" />
      <media:content medium="image" url="https://irp.cdn-website.com/683b19b1/dms3rep/multi/Vaga_CSBL_CRID.png">
        <media:description>thumbnail</media:description>
      </media:content>
      <media:content medium="image" url="https://irp.cdn-website.com/683b19b1/dms3rep/multi/Vaga_CSBL_CRID.png">
        <media:description>main image</media:description>
      </media:content>
    </item>
    <item>
      <title>Instituto Todos pela Saúde lança edital para apoiar pesquisas sobre covid-19</title>
      <link>https://www.csbiology.org/instituto-todos-pela-saude-lanca-edital-para-apoiar-pesquisas-sobre-covid-19</link>
      <description />
      <content:encoded>&lt;h3&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;span&gt;&#xD;
      
           CHAMADA PUBLICA 01/2021 - ESTUDOS DE COORTES
          &#xD;
    &lt;/span&gt;&#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    
          PRÉ-SELEÇÃO PARA CREDENCIAMENTO DE PARCEIROS
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    
          INSTITUTO TODOS PELA SAÚDE
         &#xD;
  &lt;/div&gt;&#xD;
&lt;/h3&gt;&#xD;
&lt;div&gt;&#xD;
  &lt;img src="https://irp.cdn-website.com/683b19b1/dms3rep/multi/ITpS-ec74eb51.JPG"/&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  
         O Instituto Todos pela Saúde (ITpS) inicia o processo de pré-seleção para credenciamento de grupos de pesquisa que desenvolvam estudos de coortes, conforme orientações descritas a seguir.
         &#xD;
  &lt;div&gt;&#xD;
    
          Os grupos pré-selecionados serão convocados para etapa subsequente de avaliação de propostas. Quando credenciados, os parceiros receberão recursos financeiros por um período de 2 anos, assumindo compromisso contratual para integração dos dados com o ITpS.
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;br/&gt;&#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;b&gt;&#xD;
      
           1	Objetivos do ITpS 
          &#xD;
    &lt;/b&gt;&#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    
          O ITpS tem o objetivo de obter informações de populações vacinadas e recuperadas de Covid-19, dentro de sua linha de ação “Estudos de coortes”.
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;br/&gt;&#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;b&gt;&#xD;
      
           Objetivos específicos:
          &#xD;
    &lt;/b&gt;&#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    
          i.	Responder perguntas pré-estabelecidas nesta Chamada;
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    
          ii.	Potencializar estudos já existentes de grupos de pesquisa com recursos do ITpS, particularmente na área de sequenciamento genômico;
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    
          iii.	Compartilhar expertises e especialidades entre os parceiros do ITpS para auxiliar a execução dos projetos;
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    
          iv.	Compartilhar, organizar e análisar grandes volumes de dados de Saúde para orientar a tomada de decisões estratégicas em políticas públicas.
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;br/&gt;&#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;b&gt;&#xD;
      
           2	Condições para pré-candidatura 
          &#xD;
    &lt;/b&gt;&#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    
          Podem se apresentar para pré-seleção todos os grupos de pesquisa que já desenvolvam estudos relacionados aos objetivos pré-estabelecidos para Estudos de Coortes na seção 3. Eles deverão se comprometer a adequar seus escopos, a trabalhar em rede e a compartilhar informações e dados.
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    
          Considera-se grupo candidato um conjunto de pesquisadores, de uma Instituição principal proponente, que operam cooperativamente em estudos de coortes. O grupo candidato deverá ser o gestor e responsável pelas ações necessárias para a realização dos estudos pactuados no ato do seu credenciamento, mesmo que parte das ações sejam desenvolvidas por parceiros colaboradores. 
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;br/&gt;&#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    
          Na condição de pré-candidato, o grupo deve:
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    
          i.	Demonstrar experiência no desenvolvimento de estudos de coortes de vacinados e/ou sobreviventes de Covid-19, por meio da apresentação de informações do estudo, tais como: objetivos; tamanho; características dos grupos de controle (se existentes); fonte de casos e cobertura geográfica; duração da coorte até o presente; frequência dos contatos; perguntas formuladas; testes e exames utilizados; resultados prévios (publicações ou preprints).
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    
          ii.	Possuir governança, autonomia decisória e de gestão local eficientes para desenvolver estudos referentes aos objetivos pré-estabelecidos e, para alocar pessoal e infraestrutura necessários. Isso implica na disponibilidade prévia de infraestrutura de pesquisa adequada e recursos humanos próprios;
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    
          iii.	Assumir compromisso com compartilhamento de dados na linha de ação desta chamada para que o ITpS possa elaborar macrorecomendações, em conjunto com demais parceiros e contribuir para melhorar políticas públicas, sem prejuízo de publicações de microdados do Parceiro.
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    
          Não serão elegíveis os grupos que não apresentarem recursos humanos e infraestrutura próprios, suficientes e qualificados para desenvolver estudos de coortes. Também não serão elegíveis novas coortes ainda não iniciadas e que não tenham demonstrado resultados prévios ou que apresentem dados já publicados por outros grupos ou pelo governo. 
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;br/&gt;&#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;b&gt;&#xD;
      
           3	Objetivos pré-estabelecidos para Estudos de Coortes
          &#xD;
    &lt;/b&gt;&#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    
          Os candidatos deverão apresentar, na etapa de seleção subsequente, proposta completa incluindo um Plano de Ação com estratégias para adequar seus estudos atuais para adicionar respostas para os seguintes objetivos e perguntas de pesquisa:
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;br/&gt;&#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;b&gt;&#xD;
      
           i.	Objetivo 1 – Coortes de vacinados contra Covid-19:
          &#xD;
    &lt;/b&gt;&#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    
          a.	Qual o risco de infecção/doença/hospitalização/morte pós vacina, conforme: tipo de vacina; doses recebidas; espaçamento entre doses, tempo desde a imunização; região do país; sexo, idade, etnia, comorbidades?
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    
          b.	Qual a distribuição das variantes entre os infectados que foram vacinados?
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    
          c.	Tipos e frequência de efeitos colaterais pós vacina, conforme: tipo de vacina; doses recebidas; espaçamento entre doses, tempo desde a imunização; região do país; sexo, idade, etnia, comorbidades.
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;br/&gt;&#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;b&gt;&#xD;
      
           ii.	Objetivo 2 – Coortes de sobreviventes (não vacinados) da Covid-19:
          &#xD;
    &lt;/b&gt;&#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    
          a.	Qual o risco de infecção/doença/hospitalização/morte em indivíduos recuperados de Covid-19, conforme: tempo desde o primeiro episódio; gravidade dos sintomas; região do país; sexo, idade, etnia, comorbidades?
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    
          b.	Qual a distribuição das variantes entre os recuperados?
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    
          c.	Natureza, frequência, gravidade e duração de sintomas persistentes (Covid longa).
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;br/&gt;&#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;b&gt;&#xD;
      
           4	Itens financiáveis
          &#xD;
    &lt;/b&gt;&#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    
          Os recursos financeiros aportados aos estudos de coortes pelo ITpS se destinarão exclusivamente ao custeio de despesas referentes aos seguintes itens de dispêndio: i. Bolsas; ii. Material de consumo/ insumos; iii. Viagens – Diárias, passagens e despesas de locomoção; v. Serviços de terceiros – pessoa física e pessoa jurídica; vi. Despesas de suporte operacional; vii. Outras despesas correntes.
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;br/&gt;&#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;b&gt;&#xD;
      
           5	Apresentação do candidato para credenciamento
          &#xD;
    &lt;/b&gt;&#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    
          A Instituição candidata deverá encaminhar os seguintes documentos para o e-mail
          &#xD;
    &lt;span&gt;&#xD;
      &lt;font&gt;&#xD;
        
            chamadas.itps@itps.org.br
           &#xD;
      &lt;/font&gt;&#xD;
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          , com informações submetidas em duas etapas:
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;br/&gt;&#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;b&gt;&#xD;
      
           i.	Etapa 1 – Manifestação de interesse para pré-candidatura.
          &#xD;
    &lt;/b&gt;&#xD;
    
          Envio obrigatório até às 23:59 horas, horário de Brasília/DF, do dia 29 de outubro de 2021 da Carta Consulta: documento emitido pelo responsável pela coorte, conforme modelo disponibilizado pelo ITpS (
          &#xD;
    &lt;b&gt;&#xD;
      &lt;font&gt;&#xD;
        
            link
            &#xD;
        &lt;a href="https://irp.cdn-website.com/683b19b1/files/uploaded/Modelo%20-%20Carta-Consulta%20-%20pre-selec%CC%A7a%CC%83o%20ITpS.docx" target="_blank"&gt;&#xD;
          
             aqui
            &#xD;
        &lt;/a&gt;&#xD;
      &lt;/font&gt;&#xD;
    &lt;/b&gt;&#xD;
    
          ), apresentando os seguintes conteúdos:
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    
          a.	manifestação formal de interesse no credenciamento;
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    
          b.	argumentação sintética, limitada obrigatoriamente a duas (2) páginas, trazendo a descrição da coorte de vacinados ou sobreviventes da Covid-19 em andamento;
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    
          c.	perfil resumido do grupo candidato em relação aos temas da presente Chamada, apresentado como anexo à Carta Consulta, limitado obrigatoriamente a duas (02) páginas, contendo: a experiência da equipe e o perfil dos principais pesquisadores; aspectos relevantes do sistema de gestão para atendimento dos requisitos da chamada.
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;br/&gt;&#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;b&gt;&#xD;
      
           ii.	Etapa 2 – Proposta completa.
          &#xD;
    &lt;/b&gt;&#xD;
    
          Para os candidatos pré-selecionados, será enviado convite para apresentação de proposta completa. O processo seletivo completo, contendo todas as instruções de envio da proposta e critérios de avaliação será comunicado aos candidatos pré-selecionados. 
         &#xD;
  &lt;/div&gt;&#xD;
  &lt;div&gt;&#xD;
    &lt;br/&gt;&#xD;
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&lt;/div&gt;</content:encoded>
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      <pubDate>Thu, 07 Oct 2021 15:32:23 GMT</pubDate>
      <guid>https://www.csbiology.org/instituto-todos-pela-saude-lanca-edital-para-apoiar-pesquisas-sobre-covid-19</guid>
      <g-custom:tags type="string" />
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    <item>
      <title>Mesa Redonda: CZI Grant</title>
      <link>https://www.csbiology.org/blog/mesa-redonda-czi-grant</link>
      <description>A mesa redonda com perguntas e respostas com a  Mariana Boroni (INCA), Pedro Vieira (UNICAMP) e Marcelo Mori (UNICAMP) (vejam o projeto contemplado) será no dia 25/2, 14h. Por que a análise de células</description>
      <content:encoded>&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    
                    A mesa redonda com perguntas e respostas com a  Mariana Boroni (INCA), Pedro Vieira (UNICAMP) e Marcelo Mori (UNICAMP) (vejam o 
    
  
  
                    &#xD;
    &lt;a href="https://bit.ly/3p6vDYq"&gt;&#xD;
      
                      
    
    
      projeto contemplado
    
  
  
                    &#xD;
    &lt;/a&gt;&#xD;
    
                    
  
  
    ) será no 
    
  
  
                    &#xD;
    &lt;b&gt;&#xD;
      
                      
    
    
      dia 25/2, 14h
    
  
  
                    &#xD;
    &lt;/b&gt;&#xD;
    
                    
  
  
    .
                  &#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;b&gt;&#xD;
      
                      
    
    
      Por que a análise de células únicas é importante?
    
  
  
                    &#xD;
    &lt;/b&gt;&#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    
                    Tecidos são heterogêneos e cada célula responde de forma diferente a um estímulo. Hoje é possível medir a atividade de milhares de genes dentro de células individuais de um câncer, de um pulmão de alguém infectado ou até de um olho humano. O 
    
  
  
                    &#xD;
    &lt;a href="https://www.humancellatlas.org/"&gt;&#xD;
      
                      
    
    
      Human Cell Atlas
    
  
  
                    &#xD;
    &lt;/a&gt;&#xD;
    
                    
  
  
     é um consórcio que tenta catalogar os trilhões de células humanas e assim entender melhor o que as torna tão diferentes. Ano passado tivemos o 
    
  
  
                    &#xD;
    &lt;a href="https://www.youtube.com/watch?v=-cD9P5TFlOk&amp;amp;list=PLkef4SGmngdbGgJIQh7xDI-lgMZMsl-YJ&amp;amp;ab_channel=HumanCellAtlas"&gt;&#xD;
      
                      
    
    
      Human Cell Atlas Latin America
    
  
  
                    &#xD;
    &lt;/a&gt;&#xD;
    
                    
  
  
     que mostrou que temos competência para fazer este tipo de análise.
                  &#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;b&gt;&#xD;
      
                      
    
    
      Vejam alguns vídeos sobre o que é possível fazer com single cell analysis.
    
  
  
                    &#xD;
    &lt;/b&gt;&#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;a href="https://youtu.be/DpaGcBcM338"&gt;&#xD;
      
                      
    
    
      Overview of Human Cell Atlas
    
  
  
                    &#xD;
    &lt;/a&gt;&#xD;
    
                    
  
  
     (15′)
                  &#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;a href="https://youtu.be/YJ2QX1hsH8M"&gt;&#xD;
      
                      
    
    
      Single cell for COVID-19
    
  
  
                    &#xD;
    &lt;/a&gt;&#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;a href="https://youtu.be/xS2Xf0aUeJM"&gt;&#xD;
      
                      
    
    
      Single cell genomics for microbial ecology and evolution
    
  
  
                    &#xD;
    &lt;/a&gt;&#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;a href="https://youtu.be/PRjX3-m16cw"&gt;&#xD;
      
                      
    
    
      Overview of Human Cell Atlas
    
  
  
                    &#xD;
    &lt;/a&gt;&#xD;
    
                    
  
  
     (50′)
                  &#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;a href="https://youtu.be/CVaSHbQg-P8"&gt;&#xD;
      
                      
    
    
      Resumo legal sobre single cell sequencing
    
  
  
                    &#xD;
    &lt;/a&gt;&#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;a href="https://youtu.be/R78W-g_rEpY"&gt;&#xD;
      
                      
    
    
      Minha aula sobre análise de single cell
    
  
  
                    &#xD;
    &lt;/a&gt;&#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;b&gt;&#xD;
      
                      
    
    
      Grant “Pediatric Networks for the Human Cell Atlas”
    
  
  
                    &#xD;
    &lt;/b&gt;&#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    
                    Este é um 
    
  
  
                    &#xD;
    &lt;a href="https://chanzuckerberg.com/wp-content/uploads/2021/01/Pediatric-Networks-for-HCA-Combined-Announcement-Instructions-1.pdf"&gt;&#xD;
      
                      
    
    
      edital
    
  
  
                    &#xD;
    &lt;/a&gt;&#xD;
    
                    
  
  
     da Chan Zuckerberg Initiative para realizar single cell analysis em amostras pediátricas. Vejam os objetivos:
                  &#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;b&gt;&#xD;
      
                      
    
    
      CZI Pediatric Networks grants have the following overarching scientific goals:
    
  
  
                    &#xD;
    &lt;/b&gt;&#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
     ● Generate and share data that will contribute to and establish references for organs and tissues during age windows that will clarify childhood development and maximize utility for understanding pediatric disease;
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
     ● Represent diverse ancestries in data collected, with the goal of generating references that will promote understanding of disease in populations and communities with increased incidence of childhood disease;
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
     ● Build international collaborations that promote coordinated and cohesive progress and contribute to the Human Cell Atlas;
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
     ● Identify and address shared computational or infrastructural bottlenecks, to ensure that data generated as a part of this reference can be analyzed, incorporated, and shared as a part of a global reference;
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
     ● Collect and share biospecimens, including generating and disseminating solutions for challenges associated with ancestral diversity and vulnerable status of young donors, engagement with communities and families/patients, and storing tissue for subsequent single-cell analysis; and
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
     ● Promote collaboration with other funded tissue networks and projects that are actively involved in the HCA as well as other CZI efforts, such as Rare As One, Inflammation, the Neurodegeneration Challenge Network , Essential Open Source Software, and others.
                  &#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;b&gt;&#xD;
      
                      
    
    
      Specific examples may include, but are not limited to:
    
  
  
                    &#xD;
    &lt;/b&gt;&#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
     ● Focused atlases or data generation on single organs, tissues, or multiple organs from single donors;
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
     ● Opportunities to develop and share tissue resources that will support standards, protocols, and tissue access to pediatrics researchers and clinicians; and
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
     ● Computationally focused networks that will address common challenges faced with the assembly, interpretation, and use of pediatric reference data.
                  &#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;br/&gt;&#xD;
    &lt;br/&gt;&#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;b&gt;&#xD;
      
                      
    
    
      Key Dates
    
  
  
                    &#xD;
    &lt;/b&gt;&#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
    March 30, 2021: Applications due by 5 p.m. Pacific Time
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
    July 13 – July 21, 2021: Video call interviews of finalists
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
    August 2021: Earliest notification of decisions (subject to change)
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
    October 1, 2021: Earliest start date of award period (subject to change)
                  &#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;b&gt;&#xD;
      
                      
    
    
      Budget limits:
    
  
  
                    &#xD;
    &lt;/b&gt;&#xD;
    
                    
  
  
     Because varying projects require different resourcing levels, a 
    
  
  
                    &#xD;
    &lt;b&gt;&#xD;
      
                      
    
    
      budget limit has not been set
    
  
  
                    &#xD;
    &lt;/b&gt;&#xD;
    
                    
  
  
     on a per project basis. Proposed budgets should reflect the project scope.
                  &#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;</content:encoded>
      <enclosure url="https://irp-cdn.multiscreensite.com/683b19b1/dms3rep/multi/single+cell.jpg" length="7024" type="image/jpeg" />
      <pubDate>Wed, 10 Feb 2021 11:05:00 GMT</pubDate>
      <guid>https://www.csbiology.org/blog/mesa-redonda-czi-grant</guid>
      <g-custom:tags type="string">courses</g-custom:tags>
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      <title>Workshop Estratégico – Bioinformática (Pró-Reitoria de Pesquisa da USP)</title>
      <link>https://www.csbiology.org/blog/workshop-estrategico-bioinformatica-pro-reitoria-de-pesquisa-da-usp</link>
      <description />
      <content:encoded>&lt;div data-rss-type="text"&gt;&#xD;
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  &lt;/p&gt;&#xD;
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      <pubDate>Tue, 27 Oct 2020 08:24:00 GMT</pubDate>
      <guid>https://www.csbiology.org/blog/workshop-estrategico-bioinformatica-pro-reitoria-de-pesquisa-da-usp</guid>
      <g-custom:tags type="string">courses</g-custom:tags>
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      <title>Profissionais para Projeto Federal “Desenvolver aplicativo móvel para cobertura vacinal” por bolsa-pesquisa</title>
      <link>https://www.csbiology.org/blog/profissionais-para-projeto-federal-desenvolver-aplicativo-movel-para-cobertura-vacinal-por-bolsa-pesquisa-2</link>
      <description>Venha trabalhar conosco ! Junte-se à equipe multiprofissional do Prof. Helder Nakaya de pesquisadores, alunos e desenvolvedores. Estamos no INOVA-USP trabalhando para melhorar a pesquisa e saúde no país. Ainda temos disponíveis as vagas abaixo.</description>
      <content:encoded>&lt;div data-rss-type="text"&gt;&#xD;
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                    Ainda temos disponíveis as vagas abaixo.
                  &#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    
                    Veja detalhes em: https://sites.google.com/view/csblvagas
                  &#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;</content:encoded>
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      <pubDate>Thu, 17 Sep 2020 20:02:00 GMT</pubDate>
      <guid>https://www.csbiology.org/blog/profissionais-para-projeto-federal-desenvolver-aplicativo-movel-para-cobertura-vacinal-por-bolsa-pesquisa-2</guid>
      <g-custom:tags type="string">Project</g-custom:tags>
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      <title>Workshop on Clinical Trials and Immunology</title>
      <link>https://www.csbiology.org/blog/workshop-on-clinical-trials-and-immunology</link>
      <description>This one-day workshop will teach students and researchers about the challenges and logistics involved in running clinical vaccine trials in low resource settings such as Brazil and Africa. The workshop will be interactive, which</description>
      <content:encoded>&lt;div data-rss-type="text"&gt;&#xD;
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    This one-day workshop will teach students and researchers about the challenges and logistics involved in running clinical vaccine trials in low resource settings such as Brazil and Africa. The workshop will be interactive, which means it will involve planning and reporting work with attendees, as well as group activities. 
  

  
                  &#xD;
  &lt;/p&gt;&#xD;
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&lt;div data-rss-type="text"&gt;&#xD;
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                    Organizer: 
    
  
  
                    &#xD;
    &lt;a href="http://csbiology.com/team-view/helder-nakaya/"&gt;&#xD;
      
                      
    
    
      Helder Nakaya
    
  
  
                    &#xD;
    &lt;/a&gt;&#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    
                    The professors of this workshop are:
                  &#xD;
  &lt;/p&gt;&#xD;
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&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;a href="https://www.sheffield.ac.uk/iicd/profiles/desilva"&gt;&#xD;
      
                      
    
    
      Thushan de Silva
    
  
  
                    &#xD;
    &lt;/a&gt;&#xD;
    
                    
  
  
    , M.D.m Ph.D., clinician scientist in the Vaccines and Immunity Theme and Honorary Senior Clinical Lecturer of the University of Sheffield, UK.
                  &#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
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    &lt;a href="http://www.butantan.gov.br/noticias/pesquisador-do-butantan-aborda-estudos-de-desafio-em-humanos-em-artigo-publicado-na-trials"&gt;&#xD;
      
                      
    
    
      Ricardo Palacios
    
  
  
                    &#xD;
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    ,  M.D., PhD., Manager of Clinical Research &amp;amp; Development at Butantan Institute, Brazil
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                    Date: 13/02/2020
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                    Venue: 
    
  
  
                    &#xD;
    &lt;a href="https://goo.gl/maps/NyhG9jwWXA3AHy4Y9"&gt;&#xD;
      
                      
    
    
      School of Pharmaceutical Sciences
    
  
  
                    &#xD;
    &lt;/a&gt;&#xD;
    
                    
  
  
     at USP. Block 13A, 1st floor.
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                    There are only 30 spots. Please apply by sending an email to hnakaya@usp.br with your name and position.
                  &#xD;
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&lt;/div&gt;</content:encoded>
      <enclosure url="https://irp.cdn-website.com/683b19b1/dms3rep/multi/workshop_clinical.png" length="7744" type="image/png" />
      <pubDate>Tue, 21 Jan 2020 15:47:00 GMT</pubDate>
      <guid>https://www.csbiology.org/blog/workshop-on-clinical-trials-and-immunology</guid>
      <g-custom:tags type="string">courses</g-custom:tags>
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    <item>
      <title>Annual BBQ (2019)</title>
      <link>https://www.csbiology.org/fun/annual-bbq-2019</link>
      <description />
      <content:encoded>&lt;div&gt;&#xD;
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      <pubDate>Wed, 18 Dec 2019 09:56:00 GMT</pubDate>
      <guid>https://www.csbiology.org/fun/annual-bbq-2019</guid>
      <g-custom:tags type="string" />
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      <title>The Human Cell Atlas -Brazil</title>
      <link>https://www.csbiology.org/blog/the-human-cell-atlas-brazil</link>
      <description>Brazil is going to be part of the Human Cell Atlas project. Our first meeting (in Portuguese) Workshop 1: Planning your CZI Proposal</description>
      <content:encoded>&lt;div&gt;&#xD;
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          Brazil is going to be part of the Human Cell Atlas project.
         &#xD;
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          Our first meeting (in Portuguese)
         &#xD;
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&lt;div data-rss-type="text"&gt;&#xD;
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          Workshop 1: Planning your CZI Proposal
         &#xD;
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&lt;/div&gt;</content:encoded>
      <enclosure url="https://irp-cdn.multiscreensite.com/683b19b1/HCB-BRAZIL-v4.jpg" length="118265" type="image/jpeg" />
      <pubDate>Sun, 22 Sep 2019 16:48:00 GMT</pubDate>
      <guid>https://www.csbiology.org/blog/the-human-cell-atlas-brazil</guid>
      <g-custom:tags type="string">research</g-custom:tags>
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    <item>
      <title>70 years of Disease Research</title>
      <link>https://www.csbiology.org/blog/70-years-of-disease-research</link>
      <description>This is how diseases were studied in the past 70 years. We have analyzed over 29,000,000 articles and 250GB of data.</description>
      <content:encoded>&lt;div data-rss-type="text"&gt;&#xD;
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                    This is how diseases were studied in the past 70 years. We have analyzed over 29,000,000 articles and 250GB of data.
                  &#xD;
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&lt;/div&gt;</content:encoded>
      <enclosure url="https://irp.cdn-website.com/683b19b1/dms3rep/multi/70years.png" length="10530" type="image/png" />
      <pubDate>Fri, 06 Sep 2019 20:28:00 GMT</pubDate>
      <guid>https://www.csbiology.org/blog/70-years-of-disease-research</guid>
      <g-custom:tags type="string" />
      <media:content medium="image" url="https://irp.cdn-website.com/683b19b1/dms3rep/multi/70years_csbl_blogpost-30627f4a.png">
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      <title>Ebola Tchau</title>
      <link>https://www.csbiology.org/blog/ebola-tchau</link>
      <description>Projeto de doutorado da Patrícia Gonzalez-Dias na FCF-USP.</description>
      <content:encoded>&lt;div data-rss-type="text"&gt;&#xD;
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          Projeto de doutorado da Patrícia Gonzalez-Dias na FCF-USP.
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      <pubDate>Fri, 06 Sep 2019 20:26:00 GMT</pubDate>
      <guid>https://www.csbiology.org/blog/ebola-tchau</guid>
      <g-custom:tags type="string">ebolatchau,Project,ebola</g-custom:tags>
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    <item>
      <title>Animated math</title>
      <link>https://www.csbiology.org/blog/animated-math</link>
      <description>Really cool way of explaining math!! https://www.3blue1brown.com/</description>
      <content:encoded>&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    
                    Really cool way of explaining math!!
                  &#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;a href="https://www.3blue1brown.com/"&gt;&#xD;
      
                      
    
    
      https://www.3blue1brown.com/
    
  
  
                    &#xD;
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      <pubDate>Tue, 23 Jul 2019 12:33:00 GMT</pubDate>
      <guid>https://www.csbiology.org/blog/animated-math</guid>
      <g-custom:tags type="string" />
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    <item>
      <title>Data Analysis in Global Health (July 1-2, 2019)</title>
      <link>https://www.csbiology.org/blog/data-analysis-in-global-health-july-1-2-2019</link>
      <description>The Scientific Platform Pasteur/USP (SPPU) will offer 2 parallel workshops on Data Analysis in Global Health in celebration of the Institut Pasteur International Network (RIIP) meeting – Americas. Dates: July 1st e 2nd Venue:</description>
      <content:encoded>&lt;div&gt;&#xD;
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  &lt;p&gt;&#xD;
    
                    
    
  
    The Scientific Platform Pasteur/USP  (SPPU) will offer 2 parallel workshops on Data Analysis in Global Health in celebration of the Institut Pasteur International Network (RIIP) meeting – Americas.
  

  
                  &#xD;
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      Dates: July 1
    
  
  
                    &#xD;
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        st
      
    
    
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       e 2
    
  
  
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        nd
      
    
    
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    &lt;br/&gt;&#xD;
    
                    
  
  
    Venue: INOVA-USP
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
    Av. Prof. Lúcio Martins Rodrigues, 370 – Butantã, São Paulo – SP, 05508-020, Brazil
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&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    
                    Twenty students will be accepted (10 per workshop). 
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    &lt;b&gt;&#xD;
      
                      
    
    
      Deadline for Application: June 29
    
  
  
                    &#xD;
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    &lt;sup&gt;&#xD;
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        th
      
    
    
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    &lt;br/&gt;&#xD;
    
                    
  
  
    Apply now by clicking 
    
  
  
                    &#xD;
    &lt;a href="https://forms.gle/xKQgF6jaPagdFKi59" target="_blank"&gt;&#xD;
      
                      
    
    
      here
    
  
  
                    &#xD;
    &lt;/a&gt;&#xD;
    
                    
  
  
    .
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&lt;h4&gt;&#xD;
  
                  
  Workshop I  – Viral emergence: monitoring and understanding the new challenges. 

                &#xD;
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&lt;div data-rss-type="text"&gt;&#xD;
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                    Fast human demographic expansion, reckless urbanization and
lack of sustainable development and basic sanitation are causing worldwide
anthropic environmental degradation. This comprehensive state of affairs poises
adequate conditions for the spread of pandemic viruses, (such as CHICKV, ZIKV,
WNV, etc.) and suggest that novel agents may cause problems soon (USUTU, RVFV,
EBOV, etc.). In this workshop we will focus on several topics on YFV, CHIKV and
ZIKV, which shown significant activity in Brazil during the last 5 years. 
                  &#xD;
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&lt;h4&gt;&#xD;
  
                  
  Workshop II –  Metagenomics: investigating the host-microbiome interaction through high throughput, next generation DNA sequencing.

                &#xD;
&lt;/h4&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
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                    The study of the human microbiome has revolutionized our understanding of human health and disease. Modulating the gut microbiome is on the very forefront of R&amp;amp;D aiming at maintaining health, as well as diagnosing and treating diseases. The field has advanced greatly with the implementation of new DNA sequencing technologies. This workshop will present a general view of how microbiome studies are designed and conducted, what kinds of data can be obtained, their applications and limitations. We’ll also have hands on practice on some of the basic analytical steps to start in the world of microbiome data analysis. Requirements: the attendees must bring their own laptop with R and RStudio, Putty, Chrome’s secure shell add-on and WinSCP (or mac equivalents). Some prior knowledge of Linux command line is recommended. The workshop will have 4 sessions.
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&lt;h3&gt;&#xD;
  
                  
  Workshop Program

                &#xD;
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&lt;div&gt;&#xD;
  &lt;a&gt;&#xD;
    &lt;img src="https://irp-cdn.multiscreensite.com/683b19b1/PCPUlogo.jpg" alt="" title=""/&gt;&#xD;
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      <enclosure url="https://irp-cdn.multiscreensite.com/683b19b1/Course_SPPU_2019-1170x626.png" length="54331" type="image/png" />
      <pubDate>Mon, 24 Jun 2019 16:19:00 GMT</pubDate>
      <guid>https://www.csbiology.org/blog/data-analysis-in-global-health-july-1-2-2019</guid>
      <g-custom:tags type="string">courses</g-custom:tags>
      <media:content medium="image" url="https://irp-cdn.multiscreensite.com/683b19b1/Course_SPPU_2019-1170x626.png">
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    <item>
      <title>FBC0519 2019 – Imunodiagnóstico</title>
      <link>https://www.csbiology.org/classes/fbc0519-2019-imunodiagnostico</link>
      <description>FACULDADE DE CIÊNCIAS FARMACÊUTICASDepartamento de Análises Clínicas e Toxicológicas – 2016FBC0519: Imunodiagnóstico – Integral e Noturno (4 créditos) Professores:Joilson de Oliveira MartinsEduardo Lani SilveiraHelder Takashi Imoto Nakaya Aula 1: Imunodiagnóstico das infecções bacterianas (NA)Aula</description>
      <content:encoded>&lt;div data-rss-type="text"&gt;&#xD;
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      FACULDADE DE CIÊNCIAS FARMACÊUTICAS
    
  
  
                    &#xD;
    &lt;/b&gt;&#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
    Departamento de Análises Clínicas e Toxicológicas – 2016
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
    FBC0519: Imunodiagnóstico – Integral e Noturno (4 créditos)
                  &#xD;
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&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;b&gt;&#xD;
      
                      
    
    
      Professores:
    
  
  
                    &#xD;
    &lt;/b&gt;&#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
    Joilson de Oliveira Martins
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
    Eduardo Lani Silveira
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
    Helder Takashi Imoto Nakaya
                  &#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    
                    Aula 1: Imunodiagnóstico das infecções bacterianas (NA)
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
    Aula 2: Gamopatias (NA)
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
    Aula 3: Avaliação Laboratorial de Imunodeficiências (NA)
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
    Aula 4: Imunodiagnóstico da infecção por HIV/AIDS (NA)
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
    Aula 5: Imunodiagnóstico das hepatites virais (NA)
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
    Aula 6: Infecções congênitas (rubéola, CMV, EBV) (NA)
                  &#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    
                    Todas as aulas podem ser baixadas 
    
  
  
                    &#xD;
    &lt;a href="https://drive.google.com/open?id=1L6SBaR9xq6RAvSkMp7BHFonGQzzuz3FD"&gt;&#xD;
      
                      
    
    
      aqui
    
  
  
                    &#xD;
    &lt;/a&gt;&#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
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      Temas dos seminários
    
  
  
                    &#xD;
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&lt;div data-rss-type="text"&gt;&#xD;
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    &lt;b&gt;&#xD;
      
                      
    
    
      IMUNOLOGIA DOS TRANSPLANTES
    
  
  
                    &#xD;
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  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
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                    1) Tipagem HLA e sua influência sobre o transplante de órgãos
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
    2) Mecanismos diretos e indiretos de rejeição (reconhecimento) do aloenxerto
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
    3) Detecção de anticorpos: relevância clínica após o transplante
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
    4) Reprogramando o sistema imunológico utilizando anticorpos
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
    5) Ensaios in vitro para o monitoramento imunológico de transplantes
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
    6) Uso da biologia Molecular (RT-PCR) em transplante
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
    7) Manipulação imunofarmacológica da rejeição ao enxerto
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
    8) Modelos experimentais de aterosclerose do enxerto
                  &#xD;
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&lt;div data-rss-type="text"&gt;&#xD;
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    &lt;b&gt;&#xD;
      
                      
    
    
      IMUNOLOGIA DOS TUMORES
    
  
  
                    &#xD;
    &lt;/b&gt;&#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
    1) Angiogênese e Câncer
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
    2) Estabilidade genômica e reparo do DNA
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
    3) Oncogenes de supressão tumorais
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
    4) Apoptose e morte celular
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
    5) Câncer: métodos de análise molecular
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
    6) Progressão tumoral e metástase: fatores celulares e micro-ambientais
    
  
  
                    &#xD;
    &lt;br/&gt;&#xD;
    
                    
  
  
    7) Bases celulares e moleculares do tratamento com fármacos anticâncer
    
  
  
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    &lt;br/&gt;&#xD;
    
                    
  
  
    8) Imunofarmacologia dos fármacos anticâncer
    
  
  
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    &lt;br/&gt;&#xD;
    
                    
  
  
    9) Terapia biológica para câncer
    
  
  
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    &lt;br/&gt;&#xD;
    
                    
  
  
    10) Câncer e hormônios
    
  
  
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    11) Diretrizes para o estudo dos testes diagnósticos, prognósticos e tratamentos.
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      <pubDate>Fri, 24 May 2019 13:18:00 GMT</pubDate>
      <guid>https://www.csbiology.org/classes/fbc0519-2019-imunodiagnostico</guid>
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      <title>Network Medicine</title>
      <link>https://www.csbiology.org/research/network-medicine</link>
      <description>“Given the functional interdependencies between the molecular components in a human cell, a disease is rarely a consequence of an abnormality in a single gene, but reflects the perturbations of the complex intracellular and</description>
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    “Given the functional interdependencies between the molecular components in a human cell, a disease is rarely a consequence of an abnormality in a single gene, but reflects the perturbations of the complex intracellular and intercellular network that links tissue and organ systems. The emerging tools of network medicine offer a platform to explore systematically not only the molecular complexity of a particular disease, leading to the identification of disease modules and pathways, but also the molecular relationships among apparently distinct (patho)phenotypes. Advances in this direction are essential for identifying new disease genes, for uncovering the biological significance of disease-associated mutations identified by genome-wide association studies and full-genome sequencing, and for identifying drug targets and biomarkers for complex diseases.”  
    
  
    
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    Barabási (
    
  
    
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      Nat Rev Genet
    
  
    
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    . 2011 Jan;12(1):56-68)  
  

  
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                    We have been using Network Medicine to study a broad range of infectious diseases (Chikungunya, Zika, Dengue, Yellow Fever, Tuberculosis) and inflammatory diseases (arthritis, IBD, lupus, sepsis, multiple sclerosis, among others). Also, we are applying the principles of Network Medicine for drug repositioning.
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                    In this FB post you can see how diseases were studied in the past 70 years. We have analyzed 29,000,000 articles and over 250GB of data:
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      <pubDate>Thu, 23 May 2019 07:48:00 GMT</pubDate>
      <guid>https://www.csbiology.org/research/network-medicine</guid>
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      <title>FBC0416 Fisiopatologia II (2019)</title>
      <link>https://www.csbiology.org/classes/fbc0416-fisiopatologia-ii</link>
      <description>Créditos Aula: 4 Créditos Trabalho: 0 Tipo: Semestral Objetivos O aluno deve ser capaz de descrever a fisiopatologia das principais doenças que afetam o sistema nervoso, cardiovascular, endócrino, reprodutor, além da fisiopatologia da diabetes,</description>
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      <pubDate>Fri, 10 May 2019 15:30:00 GMT</pubDate>
      <guid>https://www.csbiology.org/classes/fbc0416-fisiopatologia-ii</guid>
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      <title>FBC0536: Bioinformatics Applied to Health Sciences (2019)</title>
      <link>https://www.csbiology.org/classes/fbc0536-bioinformatics-applied-to-health-sciences-2019</link>
      <description>Course Syllabus (update February, 2019) : click here DESCRIPTION This course provides a multidisciplinary forum to discuss the impact of bioinformatics applied to life sciences. Students will learn about the latest technologies of the field,</description>
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      Course Syllabus (update February, 2019) :
    
  
  
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     click 
    
  
  
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      here
    
  
  
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      DESCRIPTION
    
  
  
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                    This course provides a multidisciplinary forum to discuss the impact of bioinformatics applied to life sciences. Students will learn about the latest technologies of the field, current progress, and will be trained in performing his/her own genomic data analyses. No computational or mathematical background is required. It is an exploratory course with emphases on development of basic bioinformatics skills, visualization, and solution of biological problems. As such, it is designed primarily for health science students interested on the application of bioinformatics as a scientific tool.
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      ORGANIZATION
    
  
  
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                    This course highlights the recent technological and methodological advances in life sciences and shows how bioinformatics can be applied to (1) investigate the molecular mechanisms underneath cellular processes and to (2) predict the behavior of biological systems. All activities, lectures and discussions involved in this course will be in English.
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                    In the beginning of the course, students will form groups of 4 to 6 people, and each group will then choose three human diseases from the list below (of which, one is going to be assigned to the group). Throughout the course, the group will utilize bioinformatics tools and specialized databases to study the selected disease. The seminar and all homework assignments should focus on the selected disease.
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                    Homework will be assigned throughout the course. A total of 3 assignments will be requested, and will be used for the final grade. Each assignment will be graded and its due date will be given to you during class (and also provided in the text below). Groups are required to send their assignment by e-mail (to csbl.usp@gmail.com) on or before the day an assignment is due. Any assignment sent later than when it is due will be graded as 0 (zero).
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      List of homework assignments:
    
  
  
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      SEMINAR
    
  
  
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                    Groups are required to present a seminar on how bioinformatics can be used to study the selected disease. The seminar should take no longer than 10 minutes.
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      EXTRA EXAM
    
  
  
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                    For those with a final grade between 3.0 and 4.9 and presence in class &amp;gt;= 70%, a supplementary exam will be provided. The student will have to write a report (max. 20 pages) showing how bioinformatics can be applied to study his/her selected topic.
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      ATTENDANCE
    
  
  
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                    Student attendance will be recorded either by signing the presence list (for regular classes) or by sending the assignment by e-mail (for homework classes). Absences for which a medical excuse is provided (professional letterhead required) will be excused.
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      <pubDate>Wed, 27 Feb 2019 14:10:00 GMT</pubDate>
      <guid>https://www.csbiology.org/classes/fbc0536-bioinformatics-applied-to-health-sciences-2019</guid>
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      <title>Annual BBQ (2018)</title>
      <link>https://www.csbiology.org/fun/annual-bbq-2018</link>
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      <pubDate>Thu, 20 Dec 2018 02:45:00 GMT</pubDate>
      <guid>https://www.csbiology.org/fun/annual-bbq-2018</guid>
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      <title>Systems Immunology and Bioinformatics Workshop, The Gambia</title>
      <link>https://www.csbiology.org/courses/systems-immunology-and-bioinformatics-workshop-the-gambia</link>
      <description>Systems Immunology and Bioinformatics Workshop, MRC Unit The Gambia at the London School of Hygiene and Tropical Medicine 19th – 23rd February 2018   Organized by Thushan de Silva Imperial College London   Supported</description>
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  Systems Immunology and Bioinformatics Workshop,
    
    
MRC Unit The Gambia at the London School of
    
    
Hygiene and Tropical Medicine

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  19th – 23rd February
    
    
2018

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      Organized by
    
  
  
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    &lt;a href="https://www.imperial.ac.uk/people/t.de-silva"&gt;&#xD;
      
                      
    
    
      Thushan de Silva
    
  
  
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                    Imperial College London
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      Supported by
    
  
  
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                    FAPESP
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                    MRC
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                    Imperial College London
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      Professors 
    
  
  
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                    Dr 
    
  
  
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    &lt;a href="http://www.imperial.ac.uk/people/m.kaforou"&gt;&#xD;
      
                      
    
    
      Myrsini Kaforou
    
  
  
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Sir Henry Wellcome Fellow, Department of Medicine, Imperial College London
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      DESCRIPTION
    
  
  
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                    The course will be focused mainly on human transcriptome analysis for systems immunology studies and lead by a collaborator of ours from Brazil, 
    
  
  
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    &lt;a href="http://csbiology.com/team-view/helder-nakaya"&gt;&#xD;
      
                      
    
    
      Helder Nakaya
    
  
  
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    . Our own head of the genomics facility Abdul Sesay and Dr. 
    
  
  
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      Myrsini Kaforou
    
  
  
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     from Imperial College London will join him to form the faculty.
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                    The course will involve 3 days of introduction to the basics of R programming, relevant R analysis and visualization packages for microarray/RNAseq analysis, other tools such as Cytoscape, Enrichr, GEO, Genemania and String which are useful for interpretation of transcriptomic data. This will mostly be hands on workshop-based sessions, but will include a few didactic lectures. This will be followed by 2 days of undertaking a systems immunology analysis project and presentation of results.
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      Location
    
  
  
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                    MRC Gambia | Medical Research Council, Fajara
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      <pubDate>Mon, 19 Feb 2018 12:04:00 GMT</pubDate>
      <guid>https://www.csbiology.org/courses/systems-immunology-and-bioinformatics-workshop-the-gambia</guid>
      <g-custom:tags type="string" />
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      <title>Modelling infectious diseases in the cell and host, Singapore</title>
      <link>https://www.csbiology.org/courses/modelling-infectious-diseases-in-the-cell-and-host-singapore</link>
      <description>22 – 24 January 2018 | Singapore, Singapore About the Workshop The principal theme of this EMBO Workshop is to understand how to model infectious diseases and their effects in the host. This is</description>
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  22 – 24 January 2018 | Singapore, Singapore

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      About the Workshop
    
  
  
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The principal theme of this 
    
  
  
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    &lt;a href="http://meetings.embo.org/event/18-infectious-disease"&gt;&#xD;
      
                      
    
    
      EMBO Workshop
    
  
  
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     is to understand how to model infectious diseases and their effects in the host. This is focused at both the cellular and whole organism level, with a goal to understanding these processes and how therapeutic strategies can be informed.
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                    Mathematical modelling is now moving forward in terms of understanding cellular processes and signalling networks. However, when these pathways are perturbed in situations such as infection then the process of modelling become orders more complex, because the whole organism has to be considered. Understanding this complexity requires data obtained from longitudinal studies and the computational power to analyse terabyte size datasets.
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                    The main objective of this EMBO Workshop is to bring together mathematical modellers, computational biologists, laboratory scientists who generate the raw data and infectious disease experts to present their most relevant research in the context of the meeting theme. The idea being to understand the predominant drivers in each field, i.e. what questions the infectious disease experts need answering, how mathematical models can achieve this, what is realistic in terms of organism biology and what types of datasets and raw information are required. A key objective is to provide a network opportunity for scientists at all stages of careers to interact in an informal setting and provide sufficient opportunity for knowledge exchange and new partnerships to develop.
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      Organizers
    
  
  
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    &lt;a href="https://www.liverpool.ac.uk/infection-and-global-health/research/respiratory-and-emerging-viruses/"&gt;&#xD;
      
                      
    
    
      Julian Hiscox
    
  
  
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University of Liverpool, UK.
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    &lt;a href="https://www.a-star.edu.sg/sign/Research/Principal-Investigators/tid/28/ng-lisa-fong-poh"&gt;&#xD;
      
                      
    
    
      Lisa Ng
    
  
  
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    &lt;br/&gt;&#xD;
    
                    
  
  
    
SIgN, A*Star, Singapore.
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      Photos
    
  
  
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      <pubDate>Mon, 22 Jan 2018 12:16:00 GMT</pubDate>
      <guid>https://www.csbiology.org/courses/modelling-infectious-diseases-in-the-cell-and-host-singapore</guid>
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      <title>Seeing Theory</title>
      <link>https://www.csbiology.org/blog/seeing-theory-2</link>
      <description>Awesome website that shows a visual introduction to probability and statistics  </description>
      <content:encoded>&lt;div data-rss-type="text"&gt;&#xD;
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                    Awesome 
    
  
  
                    &#xD;
    &lt;a href="http://students.brown.edu/seeing-theory/?vt=4"&gt;&#xD;
      
                      
    
    
      website
    
  
  
                    &#xD;
    &lt;/a&gt;&#xD;
    
                    
  
  
     that shows a visual introduction to probability and statistics
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      <pubDate>Tue, 28 Nov 2017 15:05:00 GMT</pubDate>
      <guid>https://www.csbiology.org/blog/seeing-theory-2</guid>
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      <title>Much-maligned P value</title>
      <link>https://www.csbiology.org/blog/much-maligned-p-value</link>
      <description>Nature has published a nice editorial about how “One of scientists’ favourite statistics — the P value — should face tougher standards, say leading researchers.” Read here the entire editorial. “Researchers just don’t realize</description>
      <content:encoded>&lt;div data-rss-type="text"&gt;&#xD;
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                    Nature has published a nice editorial about how “One of scientists’ favourite statistics — the P value — should face tougher standards, say leading researchers.”
                  &#xD;
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&lt;div data-rss-type="text"&gt;&#xD;
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                    Read 
    
  
  
                    &#xD;
    &lt;a href="http://www.nature.com/news/big-names-in-statistics-want-to-shake-up-much-maligned-p-value-1.22375?WT.mc_id=FBK_NatureNews&amp;amp;sf101141907=1"&gt;&#xD;
      
                      
    
    
      here
    
  
  
                    &#xD;
    &lt;/a&gt;&#xD;
    
                    
  
  
     the entire editorial.
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&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    
                    “Researchers just don’t realize how weak the evidence is when the P value is 0.05,” says Daniel Benjamin, one of the paper’s co-lead authors and an economist at the University of Southern California in Los Angeles. He thinks that claims with P values between 0.05 and 0.005 should be treated merely as “suggestive evidence” instead of established knowledge.
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      <pubDate>Wed, 26 Jul 2017 20:42:00 GMT</pubDate>
      <guid>https://www.csbiology.org/blog/much-maligned-p-value</guid>
      <g-custom:tags type="string" />
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      <title>SiPoS: Sickness Positioning System</title>
      <link>https://www.csbiology.org/blog/sipos-sickness-positioning-system</link>
      <description>  Watch video (in Portuguese):</description>
      <content:encoded>&lt;div&gt;&#xD;
  &lt;a href="https://sipos.fcf.usp.br/" target="_top"&gt;&#xD;
    &lt;img src="https://irp-cdn.multiscreensite.com/683b19b1/SiPOS_logo_final-494x360.png" alt="" title=""/&gt;&#xD;
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                    Watch video (in Portuguese):
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      <pubDate>Thu, 22 Jun 2017 18:42:00 GMT</pubDate>
      <guid>https://www.csbiology.org/blog/sipos-sickness-positioning-system</guid>
      <g-custom:tags type="string">Project</g-custom:tags>
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      <title>Social network architecture of human immune cells</title>
      <link>https://www.csbiology.org/blog/social-network-architecture-of-human-immune-cells</link>
      <description>Cool paper and cool database. http://www.immprot.org/    </description>
      <content:encoded>&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    
                    Cool 
    
  
  
                    &#xD;
    &lt;a href="https://www.nature.com/ni/journal/v18/n5/full/ni.3693.html"&gt;&#xD;
      
                      
    
    
      paper 
    
  
  
                    &#xD;
    &lt;/a&gt;&#xD;
    
                    
  
  
    and cool database.
                  &#xD;
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                    http://www.immprot.org/
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      <pubDate>Mon, 15 May 2017 20:30:00 GMT</pubDate>
      <guid>https://www.csbiology.org/blog/social-network-architecture-of-human-immune-cells</guid>
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      <title>CSBL members are the winners of Hackathon Hack4Health</title>
      <link>https://www.csbiology.org/blog/csbl-members-are-the-winners-of-hackathon-hack4health</link>
      <description>Congratulations to Matheus and Pedro for winning the 2016 Brazil Hackathon Hack4Health!! HACK4HEALTH Hackathon Hack4Health. Oriundo dos tradicionais encontros e competições de desenvolvedores do Vale do Silício, o Hospital Innovation Show (HIS) repete no Brasil</description>
      <content:encoded>&lt;div data-rss-type="text"&gt;&#xD;
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                    Congratulations to 
    
  
  
                    &#xD;
    &lt;a href="http://csbiology.com/team-view/matheus-c-burger/"&gt;&#xD;
      
                      
    
    
      Matheus
    
  
  
                    &#xD;
    &lt;/a&gt;&#xD;
    
                    
  
  
     and 
    
  
  
                    &#xD;
    &lt;a href="http://csbiology.com/team-view/pedro-russo/"&gt;&#xD;
      
                      
    
    
      Pedro
    
  
  
                    &#xD;
    &lt;/a&gt;&#xD;
    
                    
  
  
     for winning the 2016 Brazil Hackathon Hack4Health!!
                  &#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    &lt;a href="http://saudebusiness.com/his/2016/hackathon/"&gt;&#xD;
      
                      
    
    
      HACK4HEALTH
    
  
  
                    &#xD;
    &lt;/a&gt;&#xD;
  &lt;/p&gt;&#xD;
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&lt;div data-rss-type="text"&gt;&#xD;
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                    Hackathon Hack4Health. Oriundo dos tradicionais encontros e competições de desenvolvedores do Vale do Silício, o Hospital Innovation Show (HIS) repete no Brasil a Hack4Health, competição de desenvolvedores, profissionais e startups, para resolver os principais desafios do sistema de saúde.
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                    Nesse ano, quem propõe o desafio da Hackathon é a GE Healthcare e a Optum, 2 das 10 maiores empresa de TI em saúde do mundo. Debaixo do macro-tema “Big Data &amp;amp; Healthcare Analytics”, as empresas selecionaram 2 excelentes temas a serem enfrentados pelos participantes. Durante os dias 27 e 28 de setembro em São Paulo, durante o HIS, você está convidado a trabalhar para propor a melhor solução para os desafios propostos, com 2 prêmios de R$ 5.000,00 (cinco mil reais) para a melhor solução em cada desafio. Além disso, os vencedores receberão o prêmio no palco do Saúde Business Conference, recebendo o prêmio diretamente do CEO de GE Healthcare, Daurio Speranzini Jr. e do COO da Optum, Telmo Pereira , além de participar de um programa de mentoring com as empresas.
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&lt;div data-rss-type="text"&gt;&#xD;
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                    Para participar, basta preencher o formulário abaixo e aguardar a sua aprovação. Teremos um mix de participantes, sendo o foco as áreas de Tecnologia, Negócios e Saúde.
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                    As inscrições estarão abertas até o dia 11 de setembro à meia-noite e haverá uma taxa de R$ 60,00 para profissionais e R$30,00 para estudantes, a ser paga após a aprovação da inscrição.
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      <pubDate>Thu, 29 Sep 2016 14:59:00 GMT</pubDate>
      <guid>https://www.csbiology.org/blog/csbl-members-are-the-winners-of-hackathon-hack4health</guid>
      <g-custom:tags type="string" />
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      <title>Why CRISPR Gene Editing Will Change The World</title>
      <link>https://www.csbiology.org/blog/why-crispr-gene-editing-will-change-the-world</link>
      <description>Designer babies, the end of diseases, genetically modified humans that never age. Outrageous things that used to be science fiction are suddenly becoming reality. The only thing we know for sure is that things</description>
      <content:encoded>&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    
                    Designer babies, the end of diseases, genetically modified humans that never age. Outrageous things that used to be science fiction are suddenly becoming reality. The only thing we know for sure is that things will change irreversibly.
                  &#xD;
  &lt;/p&gt;&#xD;
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                  &#xD;
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  &lt;p&gt;&#xD;
    
                    Support them on Patreon so we can make more videos (and get cool stuff in return): https://www.patreon.com/Kurzgesagt?ty=h
                  &#xD;
  &lt;/p&gt;&#xD;
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      <pubDate>Fri, 02 Sep 2016 11:28:00 GMT</pubDate>
      <guid>https://www.csbiology.org/blog/why-crispr-gene-editing-will-change-the-world</guid>
      <g-custom:tags type="string" />
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      <title>Little Book of R for Bioinformatics</title>
      <link>https://www.csbiology.org/blog/little-book-of-r-for-bioinformatics</link>
      <description>Suggested by Flavio   Welcome to a Little Book of R for Bioinformatics! By Avril Coghlan, Wellcome Trust Sanger Institute, Cambridge, U.K. Email: alc@sanger.ac.uk This is a simple introduction to bioinformatics, with a focus</description>
      <content:encoded>&lt;div data-rss-type="text"&gt;&#xD;
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                    Suggested by 
    
  
  
                    &#xD;
    &lt;a href="http://csbiology.com/team-view/flavio-lichtenstein/"&gt;&#xD;
      
                      
    
    
      Flavio
    
  
  
                    &#xD;
    &lt;/a&gt;&#xD;
  &lt;/p&gt;&#xD;
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                  &#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;h1&gt;&#xD;
  
                  
  Welcome to a Little Book of R for Bioinformatics!

                &#xD;
&lt;/h1&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    
                    By 
    
  
  
                    &#xD;
    &lt;a href="http://www.sanger.ac.uk/research/projects/parasitegenomics/"&gt;&#xD;
      
                      
    
    
      Avril Coghlan
    
  
  
                    &#xD;
    &lt;/a&gt;&#xD;
    
                    
  
  
    , Wellcome Trust Sanger Institute, Cambridge, U.K. Email: 
    
  
  
                    &#xD;
    &lt;a href="mailto:alc%40sanger.ac.uk"&gt;&#xD;
      
                      
    
    
      alc@sanger.ac.uk
    
  
  
                    &#xD;
    &lt;/a&gt;&#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    
                    This is a simple introduction to bioinformatics, with a focus on genome analysis, using the R statistics software.
                  &#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    
                    To encourage research into neglected tropical diseases such as leprosy, Chagas disease, trachoma, schistosomiasis etc., most of the examples in this booklet are for analysis of the genomes of the organisms that cause these diseases.
                  &#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    
                    There is a pdf version of this booklet available at:
    
  
  
                    &#xD;
    &lt;a href="https://github.com/avrilcoghlan/LittleBookofRBioinformatics/raw/master/_build/latex/Bioinformatics.pdf"&gt;&#xD;
      
                      
    
    
      https://github.com/avrilcoghlan/LittleBookofRBioinformatics/raw/master/_build/latex/Bioinformatics.pdf
    
  
  
                    &#xD;
    &lt;/a&gt;&#xD;
    
                    
  
  
    .
                  &#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    
                    If you like this booklet, you may also like to check out my booklet on using R for biomedical statistics, 
    
  
  
                    &#xD;
    &lt;a href="http://a-little-book-of-r-for-biomedical-statistics.readthedocs.org/"&gt;&#xD;
      
                      
    
    
      http://a-little-book-of-r-for-biomedical-statistics.readthedocs.org/
    
  
  
                    &#xD;
    &lt;/a&gt;&#xD;
    
                    
  
  
    , and my booklet on using R for time series analysis, 
    
  
  
                    &#xD;
    &lt;a href="http://a-little-book-of-r-for-time-series.readthedocs.org/"&gt;&#xD;
      
                      
    
    
      http://a-little-book-of-r-for-time-series.readthedocs.org/
    
  
  
                    &#xD;
    &lt;/a&gt;&#xD;
    
                    
  
  
    .
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  &lt;/p&gt;&#xD;
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      <pubDate>Wed, 10 Aug 2016 15:17:00 GMT</pubDate>
      <guid>https://www.csbiology.org/blog/little-book-of-r-for-bioinformatics</guid>
      <g-custom:tags type="string" />
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      <title>Tarot cards for Principles of Complex Systems and Complex Networks</title>
      <link>https://www.csbiology.org/blog/tarot-cards-for-principles-of-complex-systems-and-complex-networks</link>
      <description>Suggested by Gustavo   Tarot cards for Principles of Complex Systems and Complex Networks: The full deck (so far).</description>
      <content:encoded>&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    
                    Suggested by Gustavo
                  &#xD;
  &lt;/p&gt;&#xD;
&lt;/div&gt;&#xD;
&lt;div data-rss-type="text"&gt;&#xD;
  &lt;p&gt;&#xD;
    
                     
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      <pubDate>Wed, 10 Aug 2016 15:15:00 GMT</pubDate>
      <guid>https://www.csbiology.org/blog/tarot-cards-for-principles-of-complex-systems-and-complex-networks</guid>
      <g-custom:tags type="string" />
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      <title>Hands-on Training in RNA-Seq Data Analysis</title>
      <link>https://www.csbiology.org/blog/hands-on-training-in-rna-seq-data-analysis</link>
      <description>Suggested by Flavio Hands-on Training in RNA-Seq Data Analysis I-Hsuan Lin National Yang-Ming University, Taipei, Taiwan The materials are prepared for the Next-Generation Sequencing Workshop organized by the Life Science Library Training Courses on</description>
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  Hands-on Training in RNA-Seq Data Analysis

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  I-Hsuan Lin

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      National Yang-Ming University, Taipei, Taiwan
    
  
    
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      The materials are prepared for the 
      
    
      
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       organized by the Life Science Library Training Courses on 19th Nov 2015 at Academia Sinica.
    
  
    
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    As the title suggests, RNA-Seq (RNA sequencing) utilizes the next-generation technology to assay the presence and quantity of RNA molecules in the given sample. Unlike the microarray technology that has been used since 2000s, RNA-Seq offers many advantages. This includes detects known and novel transcripts, increased specificity and sensitivity, and identification of low-abundance transcripts and isoforms with sufficient sequencing depth. RNA-seq has also been used to discover alternative splicing variants, chimeric RNAs result from fusion genes and RNA editing sites.
  

  
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      <title>ggplot2 Extensions: gallery</title>
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      <description>21 registered extensions available to explore   http://www.ggplot2-exts.org/gallery/</description>
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                    21 registered extensions available to explore
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      <title>The Elements of Bioinformatics</title>
      <link>https://www.csbiology.org/blog/the-elements-of-bioinformatics</link>
      <description>    Simply enjoy:  http://elements.eaglegenomics.com/   Click here</description>
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                    Simply enjoy:  http://elements.eaglegenomics.com/
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      <title>Human network and drug addiction</title>
      <link>https://www.csbiology.org/blog/human-network-and-drug-addiction</link>
      <description>The importance of human “connections”! (Credits at the end of the video)</description>
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                    (Credits at the end of the video)
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      <description>Post by Fernando. The world is a complicated place. Our planet is made up of millions of networks from microscopic ecosystems to global migration. How can we ever hope to understand and predict the</description>
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                    The world is a complicated place. Our planet is made up of millions of networks from microscopic ecosystems to global migration. How can we ever hope to understand and predict the complexity of our mulit-networked world? New research may have the answer…
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      <guid>https://www.csbiology.org/blog/network-earth</guid>
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      <title>Statistics for Biologists (Nature.com)</title>
      <link>https://www.csbiology.org/blog/statistics-for-biologists-nature-com</link>
      <description>Post by Flavio Lichtenstein. Image Credit: Erin DeWalt. Check out this very nice Web Collection! “There is no disputing the importance of statistical analysis in biological research, but too often it is considered only</description>
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                    Check out this very nice 
    
  
  
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      Web Collection
    
  
  
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                    “There is no disputing the importance of statistical analysis in biological research, but too often it is considered only after an experiment is completed, when it may be too late.
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                    This collection highlights important statistical issues that biologists should be aware of and provides practical advice to help them improve the rigor of their work.
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                    Nature Methods’ Points of Significance column on statistics explains many key statistical and experimental design concepts. Other resources include an online plotting tool and links to statistics guides from other publishers.”
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      <title>Union Exon Based Approach for RNA-Seq Gene Quantification</title>
      <link>https://www.csbiology.org/blog/union-exon-based-approach-for-rna-seq-gene-quantification</link>
      <description>Post by Matheus. Union Exon Based Approach for RNA-Seq Gene Quantification: To Be or Not to Be? Shanrong Zhao , Li Xi, Baohong Zhang Abstract In recent years, RNA-seq is emerging as a powerful</description>
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      Union Exon Based Approach for RNA-Seq Gene Quantification: To Be or Not to Be?
    
  
  
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                    In recent years, RNA-seq is emerging as a powerful technology in estimation of gene and/or transcript expression, and RPKM (Reads Per Kilobase per Million reads) is widely used to represent the relative abundance of mRNAs for a gene. In general, the methods for gene quantification can be largely divided into two categories: transcript-based approach and ‘union exon’-based approach. Transcript-based approach is intrinsically more difficult because different isoforms of the gene typically have a high proportion of genomic overlap. On the other hand, ‘union exon’-based approach method is much simpler and thus widely used in RNA-seq gene quantification. Biologically, a gene is expressed in one or more transcript isoforms. Therefore, transcript-based approach is logistically more meaningful than ‘union exon’-based approach. Despite the fact that gene quantification is a fundamental task in most RNA-seq studies, however, it remains unclear whether ‘union exon’-based approach for RNA-seq gene quantification is a good practice or not. In this paper, we carried out a side-by-side comparison of ‘union exon’-based approach and transcript-based method in RNA-seq gene quantification. It was found that the gene expression levels are significantly underestimated by ‘union exon’-based approach, and the average of RPKM from ‘union exons’-based method is less than 50% of the mean expression obtained from transcript-based approach. The difference between the two approaches is primarily affected by the number of transcripts in a gene. We performed differential analysis at both gene and transcript levels, respectively, and found more insights, such as isoform switches, are gained from isoform differential analysis. The accuracy of isoform quantification would improve if the read coverage pattern and exon-exon spanning reads are taken into account and incorporated into EM (Expectation Maximization) algorithm. Our investigation discourages the use of ‘union exons’-based approach in gene quantification despite its simplicity.
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      <pubDate>Thu, 12 Nov 2015 20:32:00 GMT</pubDate>
      <guid>https://www.csbiology.org/blog/union-exon-based-approach-for-rna-seq-gene-quantification</guid>
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      <title>Writing scientific articles like a native English speaker</title>
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      <description>Post by Fred. Read the paper here. Writing scientific articles like a native English speaker: top ten tips for Portuguese speakers Mariel A. Marlow “Can you identify a single colleague who has not had a</description>
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                    Read the paper 
    
  
  
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    &lt;a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935133/"&gt;&#xD;
      
                      
    
    
      here
    
  
  
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      Writing scientific articles like a native English speaker: top ten tips for Portuguese speakers
    
  
  
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Mariel A. Marlow
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                    “Can you identify a single colleague who has not had a manuscript returned with the comment “needs to be reviewed by a native English speaker”? Many researchers receive this response even after translation or revision by an official translator or a native English-speaking coauthor. Over the past four years, while conducting my doctoral, and now my postdoctoral, work here in Brazil, I have been asked to both translate and help revise numerous manuscripts for my fellow Brazilian researchers. However, despite being a native English speaker and a researcher, I have found these tasks to be quite stressful at times. The truth is, just like it is one thing to write in Portuguese and another to write well in Portuguese, the same applies to writing well in English. Furthermore, not every native English speaker who writes well in English can write well for the scientific literature. Scientific English writing has its own style and rhythm, such as the use of passive voice. Passive voice is considered poor English in most forms of writing (news, novels, blogs, etc.) outside of science. The most recent version of Microsoft Office Word will even highlight passive voice as poor grammar and ask you if you want to rephrase. However, the use of passive voice is acceptable and even encouraged in some scientific writing.
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                    Although you would expect revising an already translated paper would take less time than translating an entire manuscript, I eventually came to prefer translation. Revisions tend to take me twice as long. Online translators may be partly to blame for this phenomenon. Not only did I spend hours being frustrated by confusing phrases resulting from simple mistakes, but I also spent the majority of my time fixing the same mistakes over and over again.
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                    For this reason, I decided to assemble a compilation of the 10 most common “errors” made by native Portuguese speakers when writing scientific papers in English. I put “errors” in quotes because many of the following tips are just that: tips, or dicas. They do not always refer to incorrect English, but rather to poor English, and they are not necessarily absolute rules. Most of these are common mistakes or poor writing habits that affect even native English speakers, so correcting them before submitting your manuscript can give you an advantage with the reviewers. It may even help you to avoid the dreaded “needs to be reviewed by a native English speaker”.”
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                    Image 
    
  
  
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    &lt;a href="https://www.stthomas.edu/law/studentexperience/writingcompetitions/"&gt;&#xD;
      
                      
    
    
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      <pubDate>Mon, 21 Sep 2015 20:20:00 GMT</pubDate>
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      <title>Deep Dream Generator</title>
      <link>https://www.csbiology.org/blog/deep-dream-generator</link>
      <description>Post by Pedro. Generate your own deep dream photos and images for free. ABOUT DEEP DREAM Google has spent the last few years teaching computers how to see, understand, and appreciate our world. It’s</description>
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                    Post by 
    
  
  
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      Pedro
    
  
  
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                    Generate your own deep dream photos and images for free.
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  ABOUT DEEP DREAM

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                    Google has spent the last few years teaching computers how to see, understand, and appreciate our world. It’s an important goal that the search giant hopes will allow programs to classify images just by “looking” at them.
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      <pubDate>Fri, 11 Sep 2015 20:16:00 GMT</pubDate>
      <guid>https://www.csbiology.org/blog/deep-dream-generator</guid>
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      <title>How the hell PCA works?</title>
      <link>https://www.csbiology.org/blog/how-the-hell-pca-works</link>
      <description>Post by Pedro and Leonardo.   For those who never understood how Principal Component Analysis works… Start here. Other useful links: here here here and here.     Image credit.      </description>
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                    Post by 
    
  
  
                    &#xD;
    &lt;a href="http://csbiology.com/team-view/pedro-russo/"&gt;&#xD;
      
                      
    
    
      Pedro
    
  
  
                    &#xD;
    &lt;/a&gt;&#xD;
    
                    
  
  
     and 
    
  
  
                    &#xD;
    &lt;a href="http://csbiology.com/team-view/leonardo-r-gama/"&gt;&#xD;
      
                      
    
    
      Leonardo
    
  
  
                    &#xD;
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    .
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                    For those who never understood how Principal Component Analysis works…
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                    Start 
    
  
  
                    &#xD;
    &lt;a href="http://www.rna-seqblog.com/statquest-pca-clearly-explained/"&gt;&#xD;
      
                      
    
    
      here
    
  
  
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                    Other useful links:
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    &lt;a href="https://georgemdallas.wordpress.com/2013/10/30/principal-component-analysis-4-dummies-eigenvectors-eigenvalues-and-dimension-reduction/"&gt;&#xD;
      
                      
    
    
      here
    
  
  
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    &lt;a href="http://flowingmotion.jojordan.org/2011/12/04/down-to-earth-principal-components-analysis-in-5-steps/"&gt;&#xD;
      
                      
    
    
      here
    
  
  
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    &lt;a href="http://sebastianraschka.com/Articles/2014_pca_step_by_step.html"&gt;&#xD;
      
                      
    
    
      here
    
  
  
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                    and 
    
  
  
                    &#xD;
    &lt;a href="http://www.nature.com/nbt/journal/v26/n3/full/nbt0308-303.html"&gt;&#xD;
      
                      
    
    
      here
    
  
  
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                    Image 
    
  
  
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      <pubDate>Mon, 31 Aug 2015 20:03:00 GMT</pubDate>
      <guid>https://www.csbiology.org/blog/how-the-hell-pca-works</guid>
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      <title>Command line for dummies</title>
      <link>https://www.csbiology.org/blog/command-line-for-dummies</link>
      <description>Suggested by Pedro and Helder.   The codeacademy course for starters in command line. Check here.   Also check here (nice cheat sheet): Become a Command Line Ninja With These Time-Saving Shortcuts Image credit</description>
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                    Suggested by 
    
  
  
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      Pedro
    
  
  
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     and 
    
  
  
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    &lt;a href="http://csbiology.com/team-view/helder-nakaya/"&gt;&#xD;
      
                      
    
    
      Helder
    
  
  
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      The codeacademy course for starters in command line. 
    
  
  
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                    Check 
    
  
  
                    &#xD;
    &lt;a href="https://www.codecademy.com/en/courses/learn-the-command-line/lessons/navigation/exercises/your-first-command"&gt;&#xD;
      
                      
    
    
      here
    
  
  
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                    Also check 
    
  
  
                    &#xD;
    &lt;a href="http://lifehacker.com/5743814/become-a-command-line-ninja-with-these-time-saving-shortcuts"&gt;&#xD;
      
                      
    
    
      here
    
  
  
                    &#xD;
    &lt;/a&gt;&#xD;
    
                    
  
  
     (nice cheat sheet): 
    
  
  
                    &#xD;
    &lt;b&gt;&#xD;
      
                      
    
    
      Become a Command Line Ninja With These Time-Saving Shortcuts
    
  
  
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                    Image 
    
  
  
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    &lt;a href="http://lifehacker.com/5743814/become-a-command-line-ninja-with-these-time-saving-shortcuts"&gt;&#xD;
      
                      
    
    
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      <pubDate>Fri, 07 Aug 2015 19:57:00 GMT</pubDate>
      <guid>https://www.csbiology.org/blog/command-line-for-dummies</guid>
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      <title>R versus Python (in portuguese)</title>
      <link>https://www.csbiology.org/blog/r-versus-python-in-portuguese</link>
      <description>Post by: Leonardo Gama Navegando a altas horas da madrugada (talvez não devesse estar fazendo isso, mas tudo bem), fui parar em um artigo de um pesquisador que vêm substituindo a maioria das ferramentas que ele usa,</description>
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                    Post by: 
    
  
  
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    &lt;a href="http://csbiology.com/team-view/leonardo-r-gama/"&gt;&#xD;
      
                      
    
    
      Leonardo Gama
    
  
  
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                    Navegando a altas horas da madrugada (talvez não devesse estar fazendo isso, mas tudo bem), fui parar em 
    
  
  
                    &#xD;
    &lt;a href="http://www.talyarkoni.org/blog/2013/11/18/the-homogenization-of-scientific-computing-or-why-python-is-steadily-eating-other-languages-lunch/"&gt;&#xD;
      
                      
    
    
      um artigo
    
  
  
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     de um pesquisador que vêm 
    
  
  
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    &lt;b&gt;&#xD;
      
                      
    
    
      substituindo a maioria das ferramentas que ele usa
    
  
  
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    , baseadas em diversas linguagens, por suas correspondentes em Python.
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                    Sinceramente, desde que eu passei um dia inteiro (na sexta) tentando entender 
    
  
  
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      o básico do básico
    
  
  
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     de R para conseguir fazer um gráfico extremamente 
    
  
  
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    &lt;em&gt;&#xD;
      
                      
    
    
      simples
    
  
  
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    &lt;/em&gt;&#xD;
    
                    
  
  
    , não consigo parar de pensar que talvez seja melhor começar a fazer as coisas em Python desde já. Só nessa curta experiência, percebi algumas complicações que o mesmo pesquisador aborda 
    
  
  
                    &#xD;
    &lt;a href="http://www.talyarkoni.org/blog/2012/06/08/r-the-master-troll-of-statistical-languages/"&gt;&#xD;
      
                      
    
    
      nesse outro artigo
    
  
  
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                    Enfim, esse cara cita vários pacotes interessantes, como o 
    
  
  
                    &#xD;
    &lt;a href="https://github.com/mwaskom/seaborn"&gt;&#xD;
      
                      
    
    
      seaborn
    
  
  
                    &#xD;
    &lt;/a&gt;&#xD;
    
                    
  
  
    , que gera gráficos muito parecidos com o ggplot2 e parece ter boas funcionalidades também.
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                    Seria bom que as linguagens 
    
  
  
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      não fossem mais um obstáculo
    
  
  
                    &#xD;
    &lt;/b&gt;&#xD;
    
                    
  
  
     nesse processo, além das diferenças de formação, de interesse e de experiência inerentes a qualquer projeto interdisciplinar.
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    &lt;a href="http://funwebapp.weebly.com/web/different-types-of-programming-languages"&gt;&#xD;
      
                      
    
    
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      <pubDate>Mon, 28 Apr 2014 13:27:00 GMT</pubDate>
      <guid>https://www.csbiology.org/blog/r-versus-python-in-portuguese</guid>
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