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Data Analysis in Global Health (July 1-2, 2019)

CSBL • Jun 24, 2019

The Scientific Platform Pasteur/USP (SPPU) will offer 2 parallel workshops on Data Analysis in Global Health in celebration of the Institut Pasteur International Network (RIIP) meeting – Americas.

Dates: July 1 st e 2 nd
Venue: INOVA-USP
Av. Prof. Lúcio Martins Rodrigues, 370 – Butantã, São Paulo – SP, 05508-020, Brazil

Twenty students will be accepted (10 per workshop).
Deadline for Application: June 29 th
Apply now by clicking here.

Workshop I  – Viral emergence: monitoring and understanding the new challenges. 

Fast human demographic expansion, reckless urbanization and lack of sustainable development and basic sanitation are causing worldwide anthropic environmental degradation. This comprehensive state of affairs poises adequate conditions for the spread of pandemic viruses, (such as CHICKV, ZIKV, WNV, etc.) and suggest that novel agents may cause problems soon (USUTU, RVFV, EBOV, etc.). In this workshop we will focus on several topics on YFV, CHIKV and ZIKV, which shown significant activity in Brazil during the last 5 years. 

Workshop II –  Metagenomics: investigating the host-microbiome interaction through high throughput, next generation DNA sequencing.

The study of the human microbiome has revolutionized our understanding of human health and disease. Modulating the gut microbiome is on the very forefront of R&D aiming at maintaining health, as well as diagnosing and treating diseases. The field has advanced greatly with the implementation of new DNA sequencing technologies. This workshop will present a general view of how microbiome studies are designed and conducted, what kinds of data can be obtained, their applications and limitations. We’ll also have hands on practice on some of the basic analytical steps to start in the world of microbiome data analysis. Requirements: the attendees must bring their own laptop with R and RStudio, Putty, Chrome’s secure shell add-on and WinSCP (or mac equivalents). Some prior knowledge of Linux command line is recommended. The workshop will have 4 sessions.

Workshop Program

Workshop I 

DAY ONE – July 1 st

First section (9:00 AM to 12:00 PM)
Gonzalo Bello  –  Phylogeography of arbovirus in Brazil:  a review.
Cheik Fall and Moussa Dia –  Phylogeography of arbovirus in Africa:  a review.
Marielton Cunha Passos – The emergence of Chikungunya & reemergence of Yellow fever viruses in Brazil  

Second section (13:30 to 17:30)
Shahab Zaki Pour – Strategies for genomic sequence of Zika virus on samples with high CT
Paolo Zanotto – The evolution of viruses as superorganisms.
Denise Pilger – Drug screening & repurposing for neurotropic viruses.

DAY TWO –  July 2 nd

First section (9:00 AM to 12:00 PM)
Tatiana Ometo – My experience running a P3+ Lab at USP & CDC.
Luiz Gustavo Góes – New & old bat viruses with an impact on human health.
Angélica Campos – Neurological complications associated with influenza virus H18N11.

Second section (13:30 to 17:30)
Cristine Marie Yde Ohki – ZIKV infection on the CNS: the role of astrocytes.
Daniela Bruna de Oliveira – Longitudinal study on a case of late pregnancy by ZIKV.
Flavio Mesquita – Teaching ZIKV in the internet: My Coursera experience.

Workshop II

DAY ONE – July 1 st

First section (9:00 AM to 12:00 PM)

Prof Dr. Chris Hoffmann (USP). Studying the Microbiome: fundamental concepts; hands on practice.

Second section (13:30 to 17:30)

Dr. Fernando Amaral (Thermo Fisher). Of-shelf metagenomics solutions.

Prof Dr. Chris Hoffmann (USP). Studying the Microbiome: alpha and beta diversity based analysis; hands on practice.


DAY TWO –  July 2 nd

First section (9:00 AM to 12:00 PM)
Dr. Gregorio Manuel Iraola Bentancor (Inst. Pasteur Montevideo). Metagenomics, pathogen genomics and anti-microbial resistance.
Prof Dr. Chris Hoffmann (USP). Studying the Microbiome: statistical considerations, results interpretation and data limitations; hands on practice.

Second section (13:30 to 17:30)

Prof Dr. Chris Hoffmann (USP). Studying the Microbiome: advanced analysis and data presentation; R-based hands on practice.

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