Systems biological approaches to measure and understand vaccine immunity in humans.
Recent studies have demonstrated the utility of using systems approaches to identify molecular signatures that can be used to predict vaccine immunity in humans. Such approaches are now being used extensively in vaccinology, and are beginning to yield novel insights about the molecular networks driving vaccine immunity. In this review, we present a broad review of the methodologies involved in these studies, and discuss the promise and challenges involved in this emerging field of systems vaccinology.
Authors
Shuzhao Li; Helder I Nakaya; Dmitri A Kazmin; Jason Z Oh; Bali Pulendran
External link
Publication Year
2013
Publication Journal
Seminars in immunology
Associeted Project
Systems Vaccinology
Lista de serviços
-
Is the gut microbiome key to modulating vaccine efficacy?Is the gut microbiome key to modulating vaccine efficacy?
-
Toxicogenomic and bioinformatics platforms to identify key molecular mechanisms of a curcumin-analogue DM-1 toxicity in melanoma cells.Toxicogenomic and bioinformatics platforms to identify key molecular mechanisms of a curcumin-analogue DM-1 toxicity in melanoma cells.