Long Noncoding RNAs
Long non-coding RNAs (lncRNAs) are a type of RNA, defined as being transcripts with lengths exceeding 200 nucleotides that are not translated into protein. These molecules are crucially involved in multiple biological processes, but their role in vaccine-induced immunity and infectious diseases is still being explored. It is estimated that thousands of long non-coding RNAs (lncRNAs) are transcribed in the genome of several organisms. Yet, only a small fraction of them have been functionally characterized. Studying the expression profile of lncRNAs and how their expression correlates with the expression of protein-coding genes in various tissues and conditions will reveal interesting mechanisms of gene regulation.
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As antisense RNA gets intronic.As antisense RNA gets intronic.
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Androgen responsive intronic non-coding RNAs.Androgen responsive intronic non-coding RNAs.
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Conserved tissue expression signatures of intronic noncoding RNAs transcribed from human and mouse loci.Conserved tissue expression signatures of intronic noncoding RNAs transcribed from human and mouse loci.
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The intronic long noncoding RNA ANRASSF1 recruits PRC2 to the RASSF1A promoter, reducing the expression of RASSF1A and increasing cell proliferation.The intronic long noncoding RNA ANRASSF1 recruits PRC2 to the RASSF1A promoter, reducing the expression of RASSF1A and increasing cell proliferation.
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Antisense intronic non-coding RNA levels correlate to the degree of tumor differentiation in prostate cancer.Antisense intronic non-coding RNA levels correlate to the degree of tumor differentiation in prostate cancer.
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Insight Into the Long Noncoding RNA and mRNA Coexpression Profile in the Human Blood Transcriptome Upon Leishmania infantum Infection.Insight Into the Long Noncoding RNA and mRNA Coexpression Profile in the Human Blood Transcriptome Upon Leishmania infantum Infection.
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Long non-coding RNAs associated with infection and vaccine-induced immunityLong non-coding RNAs associated with infection and vaccine-induced immunity
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Comparative transcriptomic analysis of long noncoding RNAs in Leishmania-infected human macrophagesComparative transcriptomic analysis of long noncoding RNAs in Leishmania-infected human macrophages